PhD Opportunity in Ion Mobility Research

vor 2 Monaten

Bremen, Bremen, Deutschland Bruker Vollzeit

Overview

Bruker is recognized as a premier provider of analytical instrumentation, delivering a wide array of advanced solutions across various research and development sectors. Our commitment is to enhance product safety, expedite market readiness, and assist industries in improving quality of life. With a legacy of innovation spanning over 60 years, our global workforce of more than 6,200 professionals operates from over 90 locations worldwide.

Within Bruker R&D, our team comprises distinguished physicists, chemists, and data scientists dedicated to advancing mass spectrometry instrumentation that reveals fundamental properties of molecular systems. We maintain robust collaborations with both industrial partners and academic institutions, actively engaging in cutting-edge academic research. Our emphasis on reproducible and transparent results aligns with our support for open-source software initiatives.

The MobiliTraIN initiative is a Marie Sklodowska-Curie Action Doctoral Network focused on enhancing the fundamental understanding of ion mobility high-resolution mass spectrometry (IM-HRMS). This program aims to provide reference materials and standardization guidelines, develop advanced methodologies for IM-HRMS applications in biopharmaceutical development, biological omics research, and non-target contaminant screening, while training 13 doctoral candidates to facilitate the adoption of IM-HRMS in industry.

The MobiliTraIN network unites some of the most innovative experts in the ion mobility and mass spectrometry fields, covering a diverse range of applications from biomedicine to environmental science. This collaborative network consists of various academic and industrial partners across Europe, promoting close interactions through joint symposia and training workshops. This international scientific collaboration, coupled with direct engagement between academia and industry, provides an exceptional environment for the personal and scientific growth of emerging researchers.

Key Offerings

  • Comprehensive scientific training within an EU doctoral program.
  • Active participation in a high-visibility research project.
  • Opportunities to engage in specialized international training courses, workshops, and conferences.
  • Possibility of research visits to prestigious laboratories across Europe.
  • A distinguished three-year MSCA Fellowship.
  • Experience in the international R&D setting of a leading mass spectrometry vendor.
  • Hands-on experience in integrating fundamental research with instrument development.
  • Competitive salary for PhD candidates.
  • Annual travel allowance for research internships and attendance at international conferences and workshops.
  • Annual family allowance (if applicable).

Responsibilities

The PhD candidate will be employed by Bruker Daltonics GmbH & Co. KG and will enroll in the PhD program of a recognized university. The candidate will utilize state-of-the-art instrumentation to explore fundamental characteristics of tandem ion mobility spectrometry (TIMS) devices. Working within an interdisciplinary research and prototyping team at Bruker, the candidate will collaborate with various university research laboratories, applying gained insights to develop innovative workflows relevant to biomedicine and interpret the resulting data.

Specific responsibilities include:

  • Identifying, quantifying, and managing the impact of ions' translational temperature on their internal temperatures and potential fragmentation across different TIMS configurations.
  • Developing and demonstrating a first-order CCS determination, aligning this technique with established methods on drift tube IMS instruments.
  • Translating in-depth knowledge of TIMS technology to biomedical investigations conducted by the research labs within the doctoral network.
  • Contributing to a standardized approach for evaluating and comparing fundamental physical properties and outcomes using various ion mobility spectrometry techniques.

Qualifications

  • Master's degree or equivalent in Physics, Physical Chemistry, or a related field.
  • Experience and knowledge in one or more of the following areas: Ion mobility spectrometry, Mass spectrometry, Ion optics and physics, Python programming, Gas phase instrument development.
  • Strong analytical, logical, and innovative thinking abilities.
  • Effective communication skills and a collaborative mindset.
  • Initial experience in preparing and writing scientific publications.
  • Proficient in scientific English (oral and written).
  • Proficiency in German would be advantageous.

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