PhD Opportunity in Ion Mobility Research
vor 2 Monaten
Overview
Bruker is a premier analytical instrumentation firm that provides a wide array of advanced solutions across various research and development sectors. Our systems and instruments are meticulously designed to enhance product safety, expedite time-to-market, and assist industries in significantly improving quality of life. With a legacy of 60 years in driving innovation, we proudly employ over 6,200 professionals across more than 90 global locations.
At Bruker R&D, our team comprises leading physicists, chemists, and data scientists dedicated to advancing mass spectrometry instrumentation to uncover fundamental properties of molecular systems. We maintain a robust network of collaborations with both industrial partners and academic institutions, ensuring our active involvement in cutting-edge academic research. We are committed to reproducible and transparent results and actively support open-source software initiatives.
The MobiliTraIN initiative is a Marie Sklodowska-Curie Action Doctoral Network focused on enhancing the fundamental understanding of ion mobility high-resolution mass spectrometry (IM-HRMS). This program aims to provide reference materials and standardization guidelines, develop state-of-the-art methodologies for IM-HRMS applications in biopharmaceutical development, biological omics studies, and non-target contaminant screening, while also laying the groundwork for industrial adoption of IM-HRMS through the training of 13 doctoral candidates.
This network unites some of the most innovative thinkers in the ion mobility and mass spectrometry fields, covering a diverse range of applications from biomedicine to environmental science. It consists of various academic and industrial partners from across Europe, fostering close collaboration through joint symposia and training workshops. This strong international scientific foundation, combined with direct interactions between academia and industry, along with opportunities for research stages at different institutions, creates an ideal environment for the personal and scientific growth of emerging researchers.
Key Offerings
- Comprehensive scientific training within an EU doctoral program.
- Significant involvement in a high-visibility research project.
- Opportunities to attend specialized international training courses, workshops, and conferences.
- Possibility of research visits to renowned laboratories across Europe.
- A prestigious three-year MSCA Fellowship.
- Experience in the international R&D setting of a leading mass spectrometry vendor.
- Hands-on experience in integrating fundamental research with instrument development.
- Competitive PhD salary.
- Annual travel allowance for research internships and participation in international conferences and workshops.
- Annual family allowance (if applicable).
Responsibilities
The PhD candidate will be employed by Bruker Daltonics GmbH & Co. KG and will be enrolled in the PhD program at the Jena University Hospital. The candidate will utilize state-of-the-art instrumentation to explore fundamental characteristics of tandem ion mobility spectrometry (TIMS) devices. Within an interdisciplinary research and prototyping team at Bruker, the candidate will collaborate with other university research laboratories, applying the acquired fundamental insights to develop novel workflows relevant to biomedicine and interpret the corresponding results.
Specific responsibilities include:
- Identifying, quantifying, and managing the influence of ion translational temperature on internal temperatures and potential fragmentation across various TIMS configurations.
- Developing and demonstrating a first-order CCS determination technique, comparable to established methods on drift tube IMS instruments.
- Translating in-depth knowledge of TIMS technology to biomedical investigations conducted by the different research laboratories within the doctoral network.
- Contributing to a standardized approach for evaluating and comparing fundamental physical properties and results obtained from various ion mobility spectrometry techniques.
Qualifications
- Master's degree or equivalent in Physics, Physical Chemistry, or a related field.
- Experience and knowledge in one or more of the following areas: Ion mobility spectrometry, Mass spectrometry, Ion optics and physics, Python programming, Gas phase instrument development.
- Strong analytical, logical, and innovative thinking skills.
- Excellent communication skills and a collaborative mindset.
- Initial experience in preparing and writing scientific publications.
- Proficient scientific English language skills (oral and written).
- Fluency in German would be advantageous.
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