PhD Opportunity in Ion Mobility Research
vor 2 Monaten
Overview
Bruker, a leader in analytical instrumentation, offers a diverse range of advanced solutions across various research and development sectors. Our systems are meticulously designed to enhance product safety, expedite market readiness, and assist industries in improving quality of life. With a legacy of 60 years in driving innovation, we proudly employ over 6,200 professionals across more than 90 global locations.
At Bruker R&D, our team comprises top physicists, chemists, and data scientists dedicated to advancing mass spectrometry technology to explore the fundamental properties of molecular systems. We collaborate closely with both industrial partners and academic institutions, engaging deeply in cutting-edge research. Our commitment to reproducible and transparent results is matched by our support for open-source software initiatives.
The MobiliTraIN network, a Marie Sklodowska-Curie Action Doctoral Network, aims to enhance the understanding of ion mobility high-resolution mass spectrometry (IM-HRMS). This initiative will establish reference materials and standardization guidelines, develop innovative methods for IM-HRMS applications in biopharmaceutical development, biological omics studies, and non-target contaminant screening, while training 13 doctoral candidates.
This network unites some of the most creative minds in the ion mobility and mass spectrometry fields, addressing a wide array of applications from biomedicine to environmental science. Comprising various academic and industrial partners across Europe, the network promotes close collaboration through joint symposia and training workshops. This rich international scientific environment, coupled with direct academia-industry interaction and opportunities for research stages at different institutions, provides an ideal setting for the personal and scientific growth of emerging researchers.
Key Offerings
- Comprehensive scientific training within an EU doctoral program.
- Active participation in a high-visibility research project.
- Access to specialized international training courses, workshops, and conferences.
- Opportunity for research visits to renowned laboratories across Europe.
- Prestigious three-year MSCA Fellowship.
- Experience in a globally recognized R&D environment.
- Hands-on experience in integrating fundamental research with instrument development.
- Competitive PhD salary.
- Annual travel allowance for research internships and attendance at international conferences and workshops.
- Annual family allowance (if applicable).
Responsibilities
The PhD candidate will be employed by Bruker Daltonics GmbH & Co. KG and enrolled in the PhD program of the Jena University Hospital. Utilizing state-of-the-art instrumentation, the candidate will investigate the fundamental characteristics of tandem ion mobility spectrometry (TIMS) devices. Working within an interdisciplinary research and prototyping team at Bruker, the candidate will collaborate with university research labs to leverage fundamental insights for developing novel workflows relevant to biomedicine.
Specific Tasks Include:
- Identifying, quantifying, and controlling the effects of ions' translational temperature on their internal temperatures and potential fragmentation across various TIMS configurations.
- Developing and demonstrating a first-order CCS determination, comparable to established techniques on drift tube IMS instruments.
- Translating insights from TIMS technology to biomedical investigations conducted by different research labs within the doctoral network.
- Contributing to a standardized approach for evaluating and comparing fundamental physical properties and outcomes across different ion mobility spectrometry techniques.
Qualifications
- Master's degree or equivalent in Physics, Physical Chemistry, or a related field.
- Knowledge and experience in one or more of the following areas: Ion mobility spectrometry, Mass spectrometry, Ion optics and physics, Python programming, Gas phase instrument development.
- Strong analytical, logical, and innovative thinking skills.
- Effective communication skills and a collaborative mindset.
- Initial experience in preparing and writing scientific publications.
- Proficient in scientific English (oral and written).
- Fluency in German is advantageous.
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