PhD Student Biology, Chemistry
Vor 6 Tagen
The Medical Faculty of the Martin Luther University Halle-Wittenberg invites applications for seven positions within the mikroPank research consortium. This interdisciplinary initiative is dedicated to developing preclinical, patient-specific models to advance personalized treatments for pancreatic cancer patients.
Research Assistant / PhD Student (m-f-d) (E 13, 65 %) We are hiring:- Three PhD students (E13, 65%), reference number: -D
All positions are available immediately and are temporary, until December 31, 2027.
About the mikroPank consortium:The consortium is deticated to creating 3D tumor models from primary, patient-derived tumor cells and components of the tumor microenvironment, such as fibroblasts, adipocytes, and immune cells. These models replicate the patient-s tumor in-vitro to study mechanisms of drug resistance using advanced technologies, including single-cell RNA sequencing (scRNA-seq) and CRISPR-based genome editing. By integrating natural sciences and clinical expertise, the consortium aims to advance research towards innovative, personalized therapies for pancreatic cancer patients.
Work Tasks:- Cultivation of pancreatic tumor organoids and cells of the tumor microenvironment
- Single-cell RNA sequencing (scRNA-seq)
- Genetic manipulation of cells using CRISPR
- Independent project management
- Participation in national and international collaborations
- Opportunity for own scientific qualification
- Completed scientific university degree in the field of life sciences (Master)
- Experience with cell culture techniques, ideally experience in the culture of pan-creatic tumor organoids
- Knowledge of lentiviral transduction
- Practical experience with single-cell RNA sequencing (scRNA-seq)
- Programming experience in R is an advantage
- Scientific processing, presentation and publication of achieved results
- Very good written and spoken English language skills
- Analytical and problem-oriented thinking
- Structured and thorough way of working
- Ability to work in a team
- Collaborative research environment with communication in English
- Access to state-of-the-art equipment, facilities and resources
- Opportunities for national and international collaborations and conference visits
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