Biologist (f/m/x) - Life Sciences Researcher

Vor 2 Tagen


Leipzig, Sachsen, Deutschland Universität Leipzig, Medizinische Fakultät Vollzeit
Postdoctoral Researcher (m/f/d) - Life Sciences Institute

We are seeking a highly motivated and experienced postdoctoral researcher to join our team at the Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics. The successful candidate will investigate a novel molecular switch controlling thrombo-inflammation based on the interaction of TF (F3, tissue factor) and interferon-alpha receptor subunit 1 (IFNAR1) using cell biological, protein biochemical and in vivo approaches.

Scope of the Position:
  • Study the regulation of TF-IFNAR1 interaction and intracellular signaling in vitro and in vivo.
  • Use advanced in vitro methods, various omics approaches and innovative mouse models.
  • Perform detailed structure-function analyses based on newly generated structural data to define the molecular mechanisms as a basis for innovative diagnostic and therapeutic approaches.
Requirements:
  • Ph.D. in a biomedical field (biology, biochemistry, biotechnology, physiology, or equivalent).
  • Strong publication record that will allow them to obtain independent funding.
  • Prior experience with at least some of the methodological topics of this project: work with mice, molecular biology, protein biochemistry, flow cytometry, microscopy, immunohistochemistry.
  • Experience in thrombosis & hemostasis and/or thrombo-inflammation is desirable.
Research Environment:

The successful candidate will join a highly collaborative institute and will have access to state-of-the-art facilities for molecular biology, protein biochemistry, biophysics, pharmacology, mouse genetics, and the latest imaging applications including light sheet and FRET microscopy. The position will be embedded in the ERC-funded project TameThiFlame. The Medical Faculty is located within the University of Leipzig with direct access to numerous research facilities of the University and extramural institutes such as the Helmholtz, Max Planck and Fraunhofer Institutes.



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