Postdoc - Molecular and Bioinformatic-based

vor 5 Monaten

Duesseldorf, Deutschland Forschungszentrum Jülich Vollzeit

Would you like to contribute to sustainable data use through your work? Then the Institute of Bio
- and Geosciences - Bioinformatics (IBG-4) is the right place for you. Our team works on and develops methods and algorithms to achieve a fundamental understanding of high-dimensional data and processes in the bio-economy, focusing on e.g. data analysis, property prediction, research data management, and data integration. The position described here will be part of a project focusing on the development of biotechnological approaches to achieve carbon neutrality by combining the strengths of different scientific disciplines.

**Your Job**:

- Analyzing RNAseq data with respect to the identification and functional annotation of genes involved in, for example, cell wall degradation, carbon flux etc.
- Screening metagenomic and genomic data using deep learning methods in order to identify degrading enzymes from different data resources
- Using Hidden Markov Models and similar tools as well as machine learning for the identification of novel and better enzyme variants from a large proteome compendium
- Generating structural models of enzymes and using machine learning methods to predict their enzymatic function and characterize their molecular recognition properties
- Using machine learning methods and simulation techniques to understand environmental effects on the enzymes and improving their stability and activity
- Publishing the scientific results in international journals and traveling to national and international conferences
- (Co)-supervising PhD students

**Your Profile**:

- University degree (Master) and doctorate in bioinformatics, computer science, data science, biophysics, or life science-related fields with a proven track record in bioinformatics, biophysics, data analysis, and simulation sciences
- Very good practical experience in molecular biology, Next Generation Sequencing, and structural biology
- Extensive experience in analyzing large datasets (especially genomics, transcriptomics, metagenomics, enzyme data, and structural data)
- Knowledge in programming languages (e.g. Java, Rust, C/C++, Python) and statistical analysis using R/BioConductor/python
- Proven scientific communication skills in the form of scientific publications or equivalent
- Willingness to complement and collaborate with existing research units at the research center
- Excellent English language skills, both written and spoken are a requirement due to the international nature of the institute and collaborations

**Our Offer**:
We work on the very latest issues that impact our society and are offering you the chance to actively help in shaping the change We support you in your work with:

- A large research campus with green spaces, offering the best possible means for networking with colleagues and pursuing sports alongside work
- Outstanding scientific and technical infrastructure
- Creative and international team that conducts research at the frontiers of science
- The Forschungszentrum Jülich is one of the largest research centres in Europe with excellent scientific equipment, including the fastest supercomputer in Europe, is located on a green campus, and near the cultural centres of Cologne, Düsseldorf and Bonn
- A highly motivated group and an international and interdisciplinary working environment in one of the largest research institutions in Europe
- The possibility to develop your own research program in line with the institute and center strategy
- Flexible working hours in a full-time position with the option of slightly reduced working hours
- 30 days of annual leave and provision for days off between public holidays and weekends (e.g. between Christmas and New Year)
Targeted services for international employees, e.g. through our International Advisory Service

We offer you an exciting and varied role in an international and interdisciplinary working environment. The position is for a fixed term of 2,5 years, with possible long-term prospects. Salary and social benefits will conform to the provisions of the Collective Agreement for the Public Service (TVöD-Bund), pay group EG 13, depending on the applicant’s qualifications and the precise nature of the tasks assigned to them.

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