Postdoctoral Fellow in The Field of Molecular

vor 3 Wochen


Munich, Deutschland Deutsches Krebsforschungszentrum Vollzeit

**Position**:Postdoctoral Fellow in the field of Molecular Cancer Biology**

**Department**: DKTK partner site Munich, Department of Translational Oncology, LMU Klinikum

**Code number**:2023-0169

The German Cancer Research Center is the largest biomedical research institution in Germany. With more than 3,000 employees, we operate an extensive scientific program in the field of cancer research.

Together with university partners at seven renowned partner sites, we have established the German Cancer Consortium (DKTK).

For the newly established research department "Translational Oncology with focus on Reverse Translation" of Prof. Dr. Martin Sos at the DKTK partner site in Munich we are looking for a postdoctoral fellow in the field of molecular cancer biology. The department is located at the LMU Klinikum Großhadern.

The main goal of our research efforts is to provide breakthrough medicine for cancer patients; our projects are centered on functional understanding of molecular processes that modulate the response to cancer therapies. We employ genetically engineered mice and patient-derived models to functionally test the impact of individual genes on tumor development and the evolution of drug resistance. A focus of our work is to combine cutting-edge computational biology methods with innovative molecular cell biology methods. We aim to understand the dynamics of cellular signaling in the context of therapeutic efficacy of drugs that target specific cancer vulnerabilities in lung cancer and other tumor entities. Our lab is currently growing to establish a rich cell biology, oncology and proteomics environment and make an impact on the development of novel cancer therapies.

We offer a great environment within the lab, intensive mentoring, and multiple interactions with global leaders, both from academia and industry.

**Job description**:

- Performing functional experiments (e.g. CRISPR KO, CRISPRa, etc.) in cellular and organoid cancer models
- Collecting and analysing transcriptomic and genomic data using cutting-edge methodology
- Performing and analysing therapeutic interventions in cancer models, preferentially in mouse models
- Planning day-to-day experimental activities related to assigned research projects
- Discussing results within the team and with external collaborators
- Presenting data in regular meetings

**Requirements**:
We are looking for talented scientists driven by the desire to make a relevant contribution to the treatment of cancer patients by discovering significant findings in the lab. Profound knowledge of cancer cell biology, prior research experience and the ability to drive projects as well as a high degree of excitement are a must. The position requires a doctoral degree in a relevant field, such as molecular biology or biochemistry, and previous experience with animal models is highly recommended.

**We offer**:

- Interesting, versatile workplace
- International, attractive working environment
- Campus with modern state-of-the-art infrastructure
- Salary according to TV-L including social benefits
- Possibility to work part-time
- Flexible working hours
- Comprehensive further training program
- Access to the DKFZ International Postdoc Program

**Important notice**:
**Earliest possible start date**: as soon as possible

**Duration**:The position is initially limited to 2 years.

The position can in principle be part-time.

**Application deadline**:23.06.2023

**Contact**:
Dr. Daniela Morgenthaler
Phone +49 (0)89 4400 43962

The DKFZ is committed to increase the proportion of women in all areas and positions in which women are underrepresented. Qualified female applicants are therefore particularly encouraged to apply.



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