Phd Student in The Field of Molecular Cancer Biology

vor 2 Wochen


Munich, Deutschland Deutsches Krebsforschungszentrum Vollzeit

**Position**:PhD Student in the field of Molecular Cancer Biology**

**Department**: DKTK partner site Munich, Department of Translational Oncology, LMU Klinikum

**Code number**:2023-0202

The German Cancer Research Center is the largest biomedical research institution in Germany. With more than 3,000 employees, we operate an extensive scientific program in the field of cancer research.

Together with university partners at seven renowned partner sites, we have established the German Cancer Consortium (DKTK).

For the newly established research department "Translational Oncology with focus on Reverse Translation" of Prof. Dr. Martin Sos at the DKTK partner site Munich we are looking for a PhD Student in the field of molecular cancer biology.
The department is located at the LMU Klinikum Großhadern.

The main goal of our research efforts is to provide breakthrough medicine for cancer patients; our projects are centered on functional understanding of molecular processes that modulate the response to cancer therapies. We employ genetically engineered mice and patient-derived models to functionally test the impact of individual genes on tumor development and the evolution of drug resistance. A focus of our work is to combine cutting-edge computational biology methods with innovative molecular cell biology methods. We aim to understand the dynamics of cellular signaling in the context of therapeutic efficacy of drugs that target specific cancer vulnerabilities in lung cancer and other tumor entities. Our lab is currently growing to establish a rich cell biology, oncology and proteomics environment and make an impact on the development of novel cancer therapies.

We offer a great environment within the lab, intensive mentoring and multiple interactions with global leaders, both from academia and industry.

**Job description**:

- Performing functional experiments (e.g. CRISPR KO, CRISPRa, etc.) in cellular and organoid cancer models
- Learning and implementing novel methods to characterize cancer cells at high resolution
- Performing and analysing therapeutic interventions in cancer models including mouse models
- Planning day-to-day experimental activities relating to assigned research projects
- Discussing results within the team and with external collaborators
- Presenting data in regular meetings

**Requirements**:
We are looking for talented scientists driven by the desire to make a relevant contribution to the treatment of cancer patients by discovering significant findings in the lab. A major interest in cancer cell biology, prior research experience and a high degree of excitement are a must. The position requires a master’s degree in a relevant field, such as molecular biology or biochemistry and previous experience with animal models is highly recommended.

**We offer**:

- Interesting, versatile workplace
- International, attractive working environment
- Campus with modern state-of-the-art infrastructure
- Access to international research networks
- Doctoral student payment including social benefits
- Flexible working hours
- Comprehensive training and mentoring program through the Helmholtz International Graduate School

**Important notice**:
**Earliest Possible Start Date**: as soon as possible

**Duration**: The position is limited to 3 years.

**Application Deadline**:11.07.2023

**Contact**:
Dr. Daniela Morgenthaler
Phone +49 (0)89 4400 43962

The DKFZ is committed to increase the proportion of women in all areas and positions in which women are underrepresented. Qualified female applicants are therefore particularly encouraged to apply.



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