Phd Position in Computational Biology
vor 2 Wochen
**Position**:PhD Position in Computational Biology**
**Department**: CCU Pediatric Oncology and the Division of Pediatric Neurooncology
**Code number**:2023-0168
The German Cancer Research Center is the largest biomedical research institution in Germany. With more than 3,000 employees, we operate an extensive scientific program in the field of cancer research.
The Hopp Children's Cancer Center Heidelberg (KiTZ) is a joint institution of the German Cancer Research Center (DKFZ), the Heidelberg University Hospital (UKHD) and the University of Heidelberg (UniHD). As a treatment and research center for oncological and hematological diseases in children and adolescents, the KiTZ is committed to scientifically exploring the biology of childhood cancer and closely link promising research approaches with patient care - from diagnosis to treatment and aftercare.
The Clinical Cooperation Unit (CCU) Pediatric Oncology and the Division of Pediatric Neurooncology at the German Cancer Research Center and the Hopp Children's Cancer Center Heidelberg are jointly offering one **PhD position in computational biology for the Translational Drug Response and Genomics Profiling Project.**
The position is available in the groups “Translational Genomics” led by Dr. Robert J. Autry and “Functional Pediatric Precision Oncology” led by PD Dr. Ina Oehme.
**Job description**:
The project covers two main aspects. One aspect focuses on developing computational methods and workflows to answer clinically relevant questions across the range of childhood cancers by interrogating genomic and epi-genomic alterations. We aim to elucidate the mechanisms underlying cancer predisposition, tumorigenesis and therapeutic response to discover novel therapeutic targets and to improve diagnosis, prevention and clinical outcome in children (Autry group).
Your tasks:
- Performing genomic analyses on cancer predisposition patients and identifying novel predisposition genes on several ongoing studies directed at cancer predisposition
- Developing and maintaining drug screening pipelines and visualization methods
**Requirements**:
- Bioinformatics analytical skills and experience with Linux / Unix command line and programming languages (e.g., Python, R, and Bash) are expected as well as the willingness to expand existing knowledge.
- Experience in working in machine learning and high-performance computing environments is beneficial.
- Expertise in the analysis and integration of next-generation sequencing and other multi-omics data is a plus.
- Excellent communication skills and the ability to write publications, present research proposals and results and represent the lab at meetings and conferences.
- Excellent interpersonal skills and the ability to work independently as well as part of a team.
**We offer**:
- Interesting, versatile workplace
- International, attractive working environment
- Campus with modern state-of-the-art infrastructure
- Access to international research networks
- Doctoral student payment including social benefits
- Flexible working hours
- Comprehensive training and mentoring program through the Helmholtz International Graduate School
**Important notice**:
**Earliest Possible Start Date**: as soon as possible
**Duration**: The position is limited to 3 years with the possibility of prolongation.
**Application Deadline**:23.06.2023
**Contact**:
Dr. Robert Autry
Phone +49 (0)6221/42-3639
The DKFZ is committed to increase the proportion of women in all areas and positions in which women are underrepresented. Qualified female applicants are therefore particularly encouraged to apply.
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