Postdoctoral Position in Translational Ependymoma

vor 3 Wochen


Heidelberg, Deutschland Springer Nature Vollzeit

**Postdoctoral Position in Translational Ependymoma Research**:

- Employer- Raven51 AG (DKFZ)- Location- Heidelberg, Baden-Württemberg (DE)- Salary- Remuneration according to TV-L incl. occupational pension plan for the p.s. and capital-forming paym- Closing date- 6 Apr 2024- Discipline
Applied Science, Biomedicine, Health Science, Life Science
Job Type
Postdoctoral, Researcher
Employment - Hours
Full time
Duration
Fixed term
Qualification
Masters
Sector
Charity/NGO- You need to sign in or create an account to a job.

The German Cancer Research Center is the largest biomedical research institution in Germany. With more than 3,000 employees, we operate an extensive scientific program in the field of cancer research.

The Division of **Pediatric Neurooncology** at the German Cancer Research Center and the Hopp Children's Cancer Center Heidelberg is offering a

**Postdoctoral Position in Translational Ependymoma Research** (Ref-No. 2024-0033)

The Hopp Children's Cancer Center Heidelberg (KiTZ) is a joint institution of the German Cancer Research Center (DKFZ), the Heidelberg University Hospital (UKHD) and the University of Heidelberg (UniHD). As a treatment and research center for oncological and hematological diseases in children and adolescents, the KiTZ is committed to scientifically explore the biology of childhood cancer and closely link promising research approaches with patient care - from diagnosis to treatment and aftercare.

**Job description**:
For expansion of translational ependymoma research, you'll collaborate on groundbreaking projects with specific contributions to targeting (epi-)genetic and immunological vulnerabilities, in vitro and in vivo tumor modelling, and understanding cellular and microenvironmental mechanisms of (radio-)therapy resistance. You’ll perform and coordinate preclinical validation and prospectively oversee the translational trajectory for clinical implementation of the identified targets and approaches. This will be realized in close collaboration with other KiTZ/DKFZ groups and the KiTZ clinical trial unit. Beside further developing these projects, you’ll have the exciting opportunity to explore large multi-omic ependymoma datasets, work with established in vivo tumor model systems (both patient-derived and genetic), rely on a rich tumor sample repertoir and generate additional data using cutting-edge next-generation technologies. Availability of a dedicated state-of-the-art computing cluster for data processing and downstream analysis is available in an outstanding environment and infrastructure for (pediatric) neurooncology research. Interdisciplinary projects connecting biology with medicine and discovery with translation as well as large-scale collaborative research funding such as a currently ongoing collaborative research center (SFB) focusing on glioblastoma enrich the productive working environment. Finally, a welcoming and supportive international community of highly collaborative and aspirational colleagues will support you to achieve your scientific goals and career plans. This position is designed to advance exciting ependymoma projects, hone your molecular biology skills and foster new learning. You’ll have the autonomy to delve into related ependymoma research questions that spark your interest.

**Requirements**:

- Excellent (postdoctoral) research experience in the field of (pediatric neuro-)oncology and a strong publication record
- Expertise in (pediatric) basic and translational cancer research and hands-on experience with related wet lab and cutting-edge technologies
- Ability to plan, direct and conduct wet lab research experiments
- (Preferably) experience in the planning and execution of in vivo experiments
- Ability to manage and coordinate projects at the interface of (basic) cancer research, immunooncology, genomics / bioinformatics and clinical translation
- Independent and self-reliant way of working, characterized by a high degree of initiative and sense of responsibility
- Drive to collaborate externally and internally and work within a team to achieve shared goals, ability to supervise MD / PhD / master students
- Competence in supporting and initiating the acquisition of national and international third-party funding
- Excellent communication skills and the ability to write publications, present research proposals and results, and represent the lab at meetings and conferences
- Fluency in verbal and written English

**We offer**:

- Interesting, versatile workplace
- Excellent framework conditions: state-of-the-art equipment and opportunity for international networking at the highest level
- Remuneration according to TV-L incl. occupational pension plan for the public service and capital-forming payments
- 30 days of vacation per year
- Flexible working hours
- Possibility of mobile work and part-time work
- Family-friendly working environment, including parent-child room, counseling services, e.g. on Elder Care
- Sust



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