Research Technician: Systems Genetics
vor 3 Wochen
Research
- EMBL Heidelberg
The research group of Lars Steinmetz is seeking an outstanding, ambitious, and independently working research technician. Our group develops and applies genome-wide technologies to elucidate the genetic basis of complex phenotypes, the functions and mechanisms of transcription, and the genetic and molecular systems underlying diseases. The group works in an interdisciplinary manner across diverse projects, integrating experimental and computational biology.
Your role
The Research Technician’s responsibilities will include: - Develop CRISPR/Cas9 tools to perturb cell culture models including cardiomyocytes and immune cells, as well as mice. - Handling of human cell model systems, generation of stable cell lines, transfections, lentiviral transductions, flow cytometry, and microscopy. - Basic molecular biology techniques, including molecular cloning, DNA/RNA preparation and analysis, generation of CRISPR/Cas9 libraries for genetic screens. - Performing functional genomics screens and using cutting-edge single-cell sequencing technologies to characterize the effects of CRISPR perturbations. - Testing, developing and evaluation of new experimental protocols, in particular in the field of next generation sequencing (RNA-seq, single-cell sequencing, NGS library preparations). - The Research Technician will contribute to scientific projects at all stages, ranging from experimental design to manuscript preparation. - Working together with 1-2 dedicated senior members in the lab, as well as the EMBL Genomics Core Facility. - Training new group members and visitors in technologies and protocols used in the laboratory. Oversee supplies and equipment in the lab, routine administrative support.
**Closing date**: 10 January 2023
Contract duration: 3 year
Grading: 4-6
Reference number: HD02319
You have
Why join us
This is a fantastic opportunity to work in a team at the cutting edge of technology development in a very exciting area at a world leading institute. EMBL, Europe’s flagship laboratory for the life sciences, is an intergovernmental research institute with more than 80 independent research groups across six sites in Europe. We are an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organization with a very collegial and family friendly working environment. The remuneration package comprises a competitive salary, a comprehensive pension scheme, medical, educational and other social benefits. The Steinmetz Lab works across two sites at EMBL Heidelberg and Stanford University and is one of the world’s leading labs in technology development for functional genomics, by combining experimental work and bioinformatics.
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