Postdoctoral Researcher in Pediatric Leukemia Research

vor 2 Wochen


Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt Vollzeit
About the Position

We are seeking a highly motivated postdoctoral researcher to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our team is at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses and pioneering innovative molecularly-guided therapeutic approaches.

Key Responsibilities
  • Conduct research on novel therapeutic options in pediatric acute myeloid leukemia (AML) using Europe's largest patient-derived xenograft (PDX) biobank
  • Utilize drug, shRNA, CRISPR-Cas9 and Cas13 libraries, and state-of-the-art cellular immunotherapeutics to establish potent drug targets, drug combinations and cellular immunotherapy
  • Maintain and expand the PDX biobank, apply gene expression and single-nucleotide variants (SNV)-based characterization and perform in silico prediction of druggable targets
  • Supervise and collaborate with a research technician to ensure smooth laboratory operations
Requirements
  • PhD in life sciences or related field
  • Expertise in cell culture, flow cytometry, and molecular biology
  • Experience with mouse handling and animal experiments (FELASA certification required)
  • Ability to supervise and collaborate with a technician
  • Proficiency in spoken and written English
  • A collaborative team player with excellent communication skills
What We Offer

Collective agreement: attractive salary based on a collective agreement with an annual special payment, long-term security through company pension schemes

Collaborative spirit: excellent scientific environment, dedicated mentoring, training in novel cutting-edge techniques, collaboration opportunities with national & international world-leading laboratories

Mobility: free public transport in all Hessen (Free State Ticket Hessen)

Campus: modern cafeteria, various cafes, opportunities to rest in numerous green spaces

Work-Life-Balance: part-time employment possible, childcare in our daycare center

Health Promotion: attractive health offers, regular online and face-to-face courses on nutrition, relaxation, sports and exercise

Professional development: internal and external training for your professional development



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