Postdoctoral Researcher in Pediatric Leukemia

vor 2 Wochen


Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt Vollzeit
Postdoctoral Researcher in Pediatric Leukemia

We are seeking a highly motivated postdoctoral researcher to join our Leukemia Research Group at the Department of Pediatrics. Our team is at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses and pioneering innovative molecularly-guided therapeutic approaches.

Project Overview

The postdoctoral position aims to discover and establish novel therapeutic options in pediatric acute myeloid leukemia (AML) based on Europe's largest patient-derived xenograft (PDX) biobank for pediatric AML. The project will utilize drug, shRNA, CRISPR-Cas9 and Cas13 libraries, and state-of-the-art cellular immunotherapeutics (NK, CAR-NK, CIK, CAR-CIK, CAR-T) to establish potent drug targets, drug combinations and cellular immunotherapy that efficiently target AML in vitro and in vivo using these PDX models.

Responsibilities
  • Maintain and expand the PDX biobank
  • Apply gene expression and single-nucleotide variants (SNV)-based characterization
  • Perform in silico prediction of druggable targets based on these data sources, followed by high-throughput drug testing
  • Supervise and collaborate with a research technician to ensure smooth laboratory operations
  • Conduct flow cytometry and gene expression analysis (RNA-Seq, Western blots)
Requirements
  • PhD and publication record in life sciences or related field
  • Proficiency in spoken and written English
Benefits
  • Attractive salary based on a collective agreement with an annual special payment
  • Long-term security through company pension schemes
  • Excellent scientific environment & dedicated mentoring, training in novel cutting-edge techniques to study epigenetic mechanisms in leukemia cells, collaboration opportunities with national & international world-leading laboratories, participation in training and qualification programs of the MSNZ and the Goethe University


  • Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt Vollzeit

    Postdoctoral Researcher in Pediatric LeukemiaWe are seeking a highly motivated postdoctoral researcher to join our Leukemia Research Group at the Department of Pediatrics. Our team is at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses and pioneering innovative molecularly-guided therapeutic approaches.Project...


  • Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt Vollzeit

    Postdoctoral Researcher in Pediatric LeukemiaWe are seeking a highly motivated postdoctoral researcher to join our Leukemia Research Group at the Department of Pediatrics. Our team is at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses and pioneering innovative molecularly-guided therapeutic approaches.Project...


  • Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt Vollzeit

    Postdoctoral Researcher in Pediatric Leukemia ResearchWe are seeking a highly motivated postdoctoral researcher to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses...


  • Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt Vollzeit

    Postdoctoral Researcher in Pediatric Leukemia ResearchWe are seeking a highly motivated postdoctoral researcher to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses...


  • Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt Vollzeit

    Postdoctoral Researcher in Pediatric LeukemiaWe are seeking a highly motivated postdoctoral researcher to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses and...


  • Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt Vollzeit

    Postdoctoral Researcher in Pediatric LeukemiaWe are seeking a highly motivated postdoctoral researcher to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses and...


  • Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt Vollzeit

    Research Opportunity in Pediatric LeukemiaWe are seeking a highly motivated postdoctoral researcher to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology.Project OverviewThe project aims to discover and establish novel therapeutic options in pediatric acute myeloid leukemia...


  • Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt Vollzeit

    About the PositionWe are seeking a highly motivated postdoctoral researcher to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our team is at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses and pioneering innovative...


  • Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt Vollzeit

    About the PositionWe are seeking a highly motivated postdoctoral researcher to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our team is at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses and pioneering innovative...


  • Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt Vollzeit

    Postdoctoral Researcher in Pediatric Leukemia ResearchWe are seeking a highly motivated postdoctoral researcher to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses...


  • Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt Vollzeit

    Postdoctoral Researcher in Pediatric Leukemia ResearchWe are seeking a highly motivated postdoctoral researcher to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses...


  • Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt Vollzeit

    Postdoctoral Researcher in Pediatric Leukemia ResearchWe are seeking a highly motivated postdoctoral researcher to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses...


  • Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt Vollzeit

    Postdoctoral Researcher in Pediatric Leukemia ResearchWe are seeking a highly motivated postdoctoral researcher to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses...


  • Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt Vollzeit

    Postdoctoral Researcher in Pediatric Leukemia ResearchWe are seeking a highly motivated postdoctoral researcher to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses...


  • Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt Vollzeit

    Postdoctoral Researcher in Pediatric Leukemia ResearchWe are seeking a highly motivated postdoctoral researcher to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses...


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