PhD Student in Tumor Immunology and Immunotherapy Research

vor 3 Wochen


Freiburg, Baden-Württemberg, Deutschland Universitätsklinikum Freiburg Vollzeit

Research Opportunity in Tumor Immunology and Immunotherapy

The Department of Internal Medicine I at the Universitätsklinikum Freiburg is seeking a highly motivated PhD student to join our research group led by Jun. Prof. Natalie Köhler, PhD. Our laboratory focuses on identifying novel targets for immunotherapies in hematological malignancies, particularly key regulators of immune checkpoint molecules.

We aim to elucidate the mechanisms of and find novel therapeutic options for cancer immunotherapy-related adverse events using classical genetic mouse models and T cell characterization approaches, as well as novel NGS-based technologies.

The offered PhD project will focus on the elucidation of the immune and molecular mechanisms driving graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.

We offer:

  • an enjoyable and collaborative laboratory atmosphere with intensive mentorship
  • the opportunity to employ a wide variety of modern methods in cell-, protein- and molecular biology
  • a motivated research group
  • a translational project with clinical relevance
  • a dynamic and highly multidisciplinary research environment
  • a doctoral position (TV-L 65%) in a 3-year research project

Your skills and qualities:

  • excellent Master's degree in molecular medicine, immunology, molecular biology or a related field
  • experience in immunologic and cancer research
  • interest and knowledge in immunology and transplant biology
  • hands-on experience in cell culture and in vitro/ex vivo immunological assays
  • experience with in vivo models and FELASA certificate
  • experience in single cell transcriptomics and data analysis are a plus
  • intrinsic motivation and the ability to work in a team
  • ability to work independently
  • fluency in written and spoken English

Please submit your application online including a letter of motivation, your CV, copy of graduation certificates and University grades and one or two letters of reference. We are looking forward to your application.



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