Ph.D. Research Position in Biophysical Mechanics

vor 2 Monaten


Göttingen, Niedersachsen, Deutschland Third Institute of Physics- Uni Göttingen Vollzeit

The Third Institute of Physics at the Georg-August-Universität Göttingen is seeking to appoint a

Ph.D. Research Assistant

This role is designed for an individual to engage in cutting-edge research within the realm of biophysics, focusing on the mechanical properties of cells. The successful candidate will work on a part-time basis, with a contract duration of three years, and will receive a salary in accordance with pay grade 13 TV-L.

Key Responsibilities

The viscoelastic characteristics of cellular structures are crucial for various biological activities, including adhesion, growth, and migration. This research aims to differentiate between the passive and active mechanical properties of the cellular cortex. The project will explore the hypothesis that cellular responses to external forces occur on varying time scales, involving mechanisms such as:

  • Passive recruitment of excess surface area
  • Poroelastic relaxation of the cytosol
  • Active contraction of the cortex

The selected candidate will be responsible for integrating a micropipette aspiration system with an atomic force microscope (AFM) that is paired with a spinning disk fluorescence microscope. This innovative setup will facilitate the investigation of how the plasma membrane and actin cortex interact during controlled stretching of cellular surfaces.

Candidate Profile

Ideal applicants should possess a Master's degree in Physics, Biology, or Chemistry (or equivalent) and have experience in the biophysics of cell mechanics utilizing biological model systems. Familiarity with cellular biophysics, advanced light microscopy, and atomic force microscopy is highly desirable. The candidate should demonstrate curiosity, motivation, self-organization, and a strong interest in interdisciplinary collaboration to conduct pioneering research.

What We Offer

The Göttingen Campus is a prominent hub for neuroscience and biophysics in Europe, featuring a multitude of esteemed research institutions. The University of Göttingen is committed to equal opportunity employment and encourages applications from qualified women and individuals with disabilities, ensuring a diverse and inclusive work environment.

We invite interested candidates to submit their applications, including a cover letter, CV, copies of relevant certificates, and contact details for at least two references, preferably in a single PDF document.

This position is an excellent opportunity for aspiring researchers to contribute to significant advancements in the understanding of cellular mechanics and to develop their academic careers in a supportive environment.



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