Computational Biologist

vor 2 Wochen


Berlin, Berlin, Deutschland MDC Vollzeit

Unlocking Developmental Mysteries Through Data: Computational and Developmental Biology PhD Position

We are seeking a highly motivated and talented PhD candidate to join our dynamic research team at MDC, focusing on the cutting edge of computational biology and developmental biology. You will play a pivotal role in unraveling the complex processes governing embryonic development using advanced single-cell genomics and machine learning techniques.

Your Responsibilities:
  • Develop innovative algorithms to decipher cellular differentiation trajectories within developing embryos, leveraging time-resolved single-cell RNA sequencing, spatial transcriptomics, and lineage tracing data.
  • Harness the power of machine learning to integrate spatial transcriptomics with other data modalities, such as single-cell transcriptome profiles and advanced microscopy images.
  • Compare and contrast mouse embryonic development with a diverse range of species (e.g., human, fish, bird) and synthetic embryo models.
  • Analyze and compare the development of synthetic organoids with in vivo embryonic development.
  • Collaborate closely with experimental researchers to bridge the gap between computational analysis and biological insights.
  • Contribute actively to a highly interdisciplinary team, working alongside data scientists, computational biologists, and experimental biologists.
Your Profile:
  • Master's degree in computational or natural sciences.
  • Strong foundation in computational or quantitative methods (computational biology, bioinformatics, mathematics, or related field).
  • Proficiency in programming languages such as Python and R is essential; experience in developing efficient and reusable software is highly desirable.
  • Excellent communication skills to facilitate effective collaboration within the team and with scientific partners.
  • Solid understanding of statistical principles and hands-on experience with state-of-the-art machine learning techniques.
  • Ability to work independently and tackle challenging analytical tasks.


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