Senior Postdoc for The Division of Personalized

vor 4 Wochen


Mainz, Deutschland Deutsches Krebsforschungszentrum Vollzeit

**Reference number**:2024-0329**
- Mainz- Vollzeit- HI-TRON Mainz - Personalized Immunotherapies***

**_“Research for a life without cancer" is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and look for new cancer prevention strategies. We develop new methods with which tumors can be diagnosed more precisely and cancer patients can be treated more successfully. Every contribution counts - whether in research, administration or infrastructure. This is what makes our daily work so meaningful and exciting._**

The Helmholtz Institute HI-TRON is a collaboration of the German Cancer Research Center (DKFZ) with the Research Institute for Translational Oncology at the University Medical Center of the Johannes Gutenberg University Mainz (TRON gGmbH), the University Medical Center Mainz and the Johannes Gutenberg University Mainz. The goal of the partnership is to develop effective immunotherapies and to identify novel biomarkers for assessing the effectiveness of treatment.

To strengthen the HI-TRON team in Mainz, we are seeking a skilled and motivated

**YOUR TASKS**:

- Lead the development and optimization of LNP formulation for cell-specific biomolecule delivery, including high-throughput screening of lipid compositions and formulation parameters
- Lead the development of LNP targeting strategies using ligand conjugation, peptides, or antibodies for cell/tissue-specific delivery
- Present research findings internally and externally (national and international conferences) and publish in peer-reviewed scientific journals
- Identify new research directions, develop grant proposals, and contribute to securing external funding

**YOUR PROFILE**:

- Master's degree and PhD in pharmaceutical sciences, chemistry, bio
- or chemical engineering, or related fields
- Extensive experience in LNP formulation methods, including hands-on experience with microfluidic devices, and targeted delivery strategies, including bioconjugation techniques
- Deep knowledge in nanoparticle purification (e.g., size-exclusion chromatography, ultracentrifugation, and dialysis), and characterization (e.g. dynamic light scattering, and Cryo-EM)
- Strong background in relevant in vitro and in vivo models and approaches for evaluating key parameters of nanoparticles, such as efficacy, biodistribution, and toxicity
- Proven publication record in high-impact journals related to biological therapeutics and nanomedicine
- Meticulous, quality-focused, and able to work independently while consistently meeting deadlines with a high degree of accuracy and efficiency
- Strong written and oral communication skills in English with effective interpersonal skills that foster teamwork and collaboration

**WE OFFER**:
**Excellent framework conditions: state-of-the-art equipment and opportunities for international networking at the highest level**

***:
**Remuneration according to TV-L incl. occupational pension plan and capital-forming payments**

***:
**30 days of vacation per year**

***:
**Flexible working hours**

***:
**Possibility of part-time work**

***:
**Family-friendly working environment**

***:
**Sustainable travel to work: subsidized Germany job ticket**

***:
**Our Corporate Health Management Program offers a holistic approach to your well-being**

***:
**Develop your full potential: access to the DKFZ International Postdoc Program and DKFZ Career Service with targeted offers for your personal development to further develop your talents**

***:
**ARE YOU INTERESTED?**:
Then become part of the DKFZ and join us in contributing to a life without cancer

**Contact**:
Dr. Ibrahim Murathan Sektioglu
Phone: +49 (0)6131/179816

**Duration**: The position is limited to 3 years with the possibility of prolongation.**Application Deadline**:26.11.2024



  • Mainz, Deutschland Deutsches Krebsforschungszentrum DKFZ Vollzeit

    “Research for a life without cancer” is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and look for new cancer prevention strategies. We develop new methods with which tumors can be diagnosed more precisely and cancer patients can be treated more successfully. Every contribution counts...


  • Mainz, Deutschland Deutsches Krebsforschungszentrum (DKFZ) Vollzeit

    “Research for a life without cancer” is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and look for new cancer prevention strategies. We develop new methods with which tumors can be diagnosed more precisely and cancer patients can be treated more successfully. Every contribution counts...


  • Mainz, Deutschland Deutsches Krebsforschungszentrum DKFZ Vollzeit

    “Research for a life without cancer” is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and look for new cancer prevention strategies. We develop new methods with which tumors can be diagnosed more precisely and cancer patients can be treated more successfully. Every contribution counts...


  • Mainz, Deutschland DKFZ Vollzeit

    Senior Postdoc for the Division of Personalized Immunotherapies Reference number: 2024-0329 Mainz Vollzeit HI-TRON Mainz - Personalized Immunotherapies “Research for a life without cancer" is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and...


  • Mainz, Rheinland-Pfalz, Deutschland DKFZ Vollzeit

    Lipid Nanoparticle Formulation Expert for Cell-Specific Biomolecule DeliveryAt the German Cancer Research Center (DKFZ), we are seeking a skilled and motivated senior postdoc to lead the development and optimization of lipid nanoparticle formulation for cell-specific biomolecule delivery.Your TasksDevelop and optimize LNP formulation for cell-specific...

  • Academic staff member

    vor 2 Stunden


    Mainz, Deutschland Johannes Gutenberg-Universität Mainz Vollzeit

    Johannes Gutenberg-Universität Mainz (JGU) [❮]() [❯]() Johannes Gutenberg University Mainz (JGU) is one of the largest universities in Germany. Thanks to its location in the Rhine-Main science region, the university can unfold to its full potential and showcase its innovative power and dynamism. Its status as a comprehensive university allows for...


  • Mainz, Deutschland Proclinical Vollzeit

    Proclinical are recruiting for a Director of Clinical Operations to join a biotech organisation. This role is on a permanent basis and is located in Germany. **Responsibilities**: - Monitor actions connected to the heading of the project teams, the oversight/control of third-party providers, the performance of all services in a timely manner as well as...


  • Mainz, Rheinland-Pfalz, Deutschland Deutsches Krebsforschungszentrum (DKFZ) Vollzeit

    AnforderungenWir suchen einen Senior Postdoc für unsere Division Personalisierte Immuntherapien. Der Kandidat sollte über einen starken Hintergrund in der LNP-Formulierung verfügen und eine Leidenschaft für die Entwicklung innovativer Plattformen haben.AufgabenDie Entwicklung und Optimierung von LNP-Formulierungen für zell-spezifische...


  • Mainz, Rheinland-Pfalz, Deutschland SCHOTT Vollzeit

    About the RoleWe are seeking a highly skilled Senior Manager to lead our medical technology innovation efforts. As part of our New Venture team, you will be responsible for identifying and developing business opportunities in the medical/life sciences space.

  • Director of Gm&e Sales

    vor 7 Monaten


    Mainz, Deutschland Hilton Vollzeit

    Director of GM&E Sales (m/w/d) A GM&E Sales Manager manages the hotel sales in GM&E by recommending growth efforts, monitoring progress, and ensuring that the hotel is competitively positioned within the local marketplace. **What will I be doing?** As Director of GM&E Sales, you are responsible for working closely with the Senior Management Team to drive...


  • Mainz, Deutschland Institut für Molekulare Biologie gGmbH Vollzeit

    **About us**: **Background** Human brain development is spatially and temporally tightly controlled, with sequential and precise orchestrated cellular and molecular programs. Any perturbation in these progresses can lead to detrimental effects. For example, mutations in genes encoding for epigenetic regulators, especially for the BAF chromatin remodeling...


  • Mainz, Deutschland Institut für Molekulare Biologie gGmbH Vollzeit

    **About us**: **Background** Human brain development is spatially and temporally tightly controlled, with sequential and precise orchestration of cellular and molecular programs. Any perturbation in these molecular programs can lead to detrimental effects. For example, mutations in genes encoding epigenetic regulators, especially the BAF chromatin...

  • Director of Gm&e Sales

    vor 7 Monaten


    Mainz, Deutschland Hilton Vollzeit

    A GM&E Sales Manager manages the hotel sales in GM&E by recommending growth efforts, monitoring progress, and ensuring that the hotel is competitively positioned within the local marketplace. **What will I be doing?** As Director of GM&E Sales, you are responsible for working closely with the Senior Management Team to drive business needs and expand...


  • Mainz, Rheinland-Pfalz, Deutschland REDNET GmbH Karriere Vollzeit

    **Job Title:** Senior Software Developer for a Leading Tech FirmWe are seeking a highly skilled Senior Software Developer to join our team at a leading tech firm. The successful candidate will be responsible for designing, developing, and maintaining complex software systems.**Key Responsibilities:**Design and develop software systems using modern...


  • Mainz, Rheinland-Pfalz, Deutschland Hochschule Trier - Trier University of Applied Sciences Vollzeit

    About the Role:We are seeking a highly skilled Senior Software Engineer to join our team. The successful candidate will be responsible for designing and implementing high-level software solutions.Key Responsibilities:Develop and maintain high-quality software codeCollaborate with cross-functional teams to identify and prioritize project requirementsDesign...


  • Mainz, Deutschland Shared Service Center - Mainz Vollzeit

    Summary WE CARE FOR PEOPLE SO THEY CAN BE THEIR BEST. At Hyatt Services GmbH, diversity is not just a buzzword; it's the cornerstone of our success. With a team of over 200 employees hailing from an impressive 52 different countries, our workplace thrives on a rich tapestry of perspectives and experiences. We believe that embracing this global mosaic fuels...

  • (Senior) Sales Manager

    vor 8 Monaten


    Mainz, Deutschland Lineas Vollzeit

    ‒ Responsible for sales with existing customers and new customers ‒ Make complex commercial offers, negotiate the terms with the customer and write the contract for both renewals as new business opportunities ‒ Initiate modal shift solutions ‒ Capable of digesting market information to translate into strategy ‒ Look for new contacts,...


  • Mainz, Rheinland-Pfalz, Deutschland AWO Bezirksverband Rheinland e.V. Vollzeit

    We are seeking a skilled Senior Software Engineer to join our team. The successful candidate will be responsible for designing and implementing backend development solutions. Key responsibilities include:Collaborating with cross-functional teams to identify and prioritize project requirementsDesigning and developing scalable and efficient backend...


  • Mainz, Deutschland Proclinical Vollzeit

    Proclinical are recruiting for a Global Medical Affairs, Infectious Diseases Administrator to join a biotech organisation. This role is on a permanent basis. *** **Responsibilities**: - Supervise divisional procedures and SOPs and notify owners when documents are due to update, which involves being in line with any other divisions for evaluations, etc. -...

  • Sr. Clerk

    vor 6 Monaten


    Mainz-Kastel, Deutschland Bank of America Vollzeit

    Requisition #1767 **Senior Clerk - Item Processing position located at Mainz-Kastel District Office, Full-time 40 hrs.**M/F/d** I. Summary This position is responsible for actively participating in all functions which are performed within the Item Processing department and may assume responsibility for the section in the absence of the Chief Clerk....