Phd Student

vor 4 Wochen


Oldenburg, Deutschland Carl von Ossietzky Universität Oldenburg Vollzeit

The Department of Medical Microbiology and Virology at the University of Oldenburg is seeking a highly motivated

**PhD student (M/F/d)**
**(salary according to E 13 TV-L, 65% of regular working hours)**

**as soon as possible** for a limited period of three years. The advertised position is also suitable for part-time work.

**The project**:
To prevent us from viral infections, host cells are equipped with a panoply of antiviral mechanisms including the group of interferon-stimulated genes (ISGs) that provide a robust first line of defense. However, for hepatitis E virus (HEV) which the most common cause of acute viral hepatitis worldwide it remains elusive which ISGs are critical to control HEV infection. Therefore, we have performed a high-throughput screen to identify ISGs with anti-HEV activity. The PhD project will take advantage of these data to focus on a molecular characterization of novel cellular restriction factors and their potential role for HEV pathogenesis.

**Responsibilities**:

- Conduct experiments under BSL-2 conditions, including cell culture, fluorescence and confocal microscopy, immunoprecipitations, molecular cloning
- Data processing (image analysis and statistical analysis)
- Data presentation

**Your profile**:

- An academic university degree (diploma (Uni) / Master or equivalent) in virology, biomedicine, molecular biology or related sciences (human medicine)
- Laboratory experience in the field of molecular or cell biology
- Social competence and excellent team skills
- Motivation and flexibility, a high degree of dedication and productivity
- Excellent communication skills in English

**We offer**:

- Working in a highly motivated research group
- Working in a DFG-funded project with multiple collaborators
- Possibilities to attend national and international conferences
- Well equipped BSL-2 facility
- Flexible working hours and workplace design


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