Doctoral Researcher/phd Student

vor 2 Monaten

Marburg an der Lahn, Deutschland Universität Marburg Vollzeit

**registration number**: fb16-0005-wmz-2024

**Entry date**:
as soon as possible

**Application deadline**:
2024-03-03

**Salary**:
E 13 TV-H

**Duration**:
3 years

**Volume of employment**:
part-time (65 %)

The University of Marburg, founded in 1527, offers a variety of excellent programs of study for around 22,000 students and confronts the important topics of our time through excellent research across a broad spectrum of sciences.

Doctoral Researcher/PhD Student

The position is offered for a period of 3 years, if no former times of qualification must be considered, and is conducted part-time (65 % of regular working hours), with salary and benefits commensurate with a public service position in the state Hesse, Germany (TV-H E 13, 65 %).

The research group of Dr. Benedict Tan, situated within the Institute of Pharmaceutical Chemistry, aims to understand fundamental principles of mitochondrial gene expression, and how defects to this process contribute to a variety of rare human diseases. We study this primarily by reconstituting key molecular events in vitro, and by combining this with cell culture methods to establish the in vivo context of our work.

**Tasks**:

- scientific services in research and teaching, in particular expression and purification of recombinant proteins
- perform biochemical assays that reconstitute key steps in human mitochondrial RNA metabolism in vitro
- corroborate biochemical findings using biochemical and genetic methods in cultured human cells
- perform genetic and proteomic screens to identify new players in mitochondrial gene expression
- thoroughly record, analyse, and present scientific data
- drive an independent research project under the direct supervision of the principal investigator (PI)

The position is limited to a time period deemed adequate for the completion of a doctoral degree. As part of the assigned duties, there will be ample opportunity to conduct the independent scientific research necessary for the completion of a doctorate. The limitation complies to - 2, 1 WissZeitVG.

**Profile**:

- MSc-degree or equivalent in biochemistry, molecular biology, genetics or a related field
- proficiency in written and spoken English
- excellent problem-solving skills and collaborative work ethic
- passion for curiosity-driven science
- experience in molecular cloning, protein purification, in vitro transcripton, and cell culture techniques (e.g., transient transfection, siRNA-mediated knockdown) is desirable
- a background in transcription and nucleic acid biochemistry is advantageous

Contact for more Information

Dr. Benedict G. Tan

+49 6421-28 25553

We support women and strongly encourage them to apply. In areas where women are underrepresented, female applicants will be preferred in case of equal qualifications. As a certified family-friendly university, we support our employees in balancing family and career. A reduction of working time is possible. Applicants with a disability as discribed in SGB IX (- 2 Abs. 2, 3) will be preferred in case of equal qualifications. Application and interview costs can not be refunded.

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