Research Scientist

Vor 3 Tagen

Hamburg, Deutschland Evotec Vollzeit

At Evotec’s headquarters in Hamburg, Germany, the Translational Biology department is seeking a highly motivated and dedicated

Research Scientist (all genders)

Neurodegeneration Research

Full-time and permanent

Your key responsibilities:
- Establish and implement readouts for protein quantification, protein folding and protein quality control pathways- Develop and supervise cellular assay systems based on iPSC neurons and neuronal cell lines- Participate in cross-functional teams to support preclinical drug discovery with the potential to lead projects in the early drug discovery stages- Plan, organize and supervise the work of technical staff- Train and support staff in development of technical skills

Your ideal qualifications:
- PhD in Neurobiology or a related field with focus on neurodegenerative diseases and some years of professional experience- Good understanding of protein biochemistry, protein (mis)folding and protein aggregation biology- Experience with Immunoassays (e.g. TR-FRET, MSD, ELISA) and Immunocytochemistry (ICC)- Substantial experience with assays based on neuronal cell cultures, ideally iPSC-derived neurons- Proven excellence in biochemical assay development and a mindset to tweak and optimize assay parameters until highly reproducible and quality-controlled assay results are achieved- Experience with Omics datasets (e.g. Transcriptomics, Proteomics) analysis would be a plus- Track record of collaborating with other scientists- High degree of initiative and flexibility, with the ability to deliver results under challenging timelines- Good organizational skills and the ability to lead a small group of technical assistants- Good English verbal and written communication skills, German advantageous- Strong publication record and demonstrated experience in conducting independent research

Our offer:
- A position within a vigorous and exciting professional environment promoted by an open culture and a spirit of community- A diverse, international workforce with a dynamic working environment that fosters creativity, innovations and teamwork- 30 days of annual holiday, monthly allowance for public transportation, and in-house canteen- Capital forming benefits, flexible working hours, holiday pay, and annual bonus depending on performance

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