Senior Scientist

vor 1 Woche


Martinsried, Deutschland CRELUX GmbH Vollzeit

**CRELUX führt für Auftraggeber aus der Pharma - und Biotech** **Industrie strukturbasierte Wirkstoffforschung durch. Wir sind** **Teil von Wuxi AppTec, eine der weltweit führenden** **Auftragsforschungsinstituten mit 28 Standorten und mehr als** **40.000 Mitarbeitern weltweit.** **Wir bieten unseren Partnern seit vielen Jahren eine breite** **Palette an Forschungsdienstleistungen zu Hit-Finding und Lead-** **Optimierung: Herstellung rekombinanter Proteine,** **biophysikalische Assays, Fragment-Screening, DEL-Screening und** **Strukturanalyse biomolekularer Targets. Wir haben uns voll der** **Verwirklichung unserer Vision "every drug can be made and** **every disease can be treated" verschrieben.** **CRELUX GmbH** **Am Haag 16** **82166 Gräfelfing** **Role : Senior Scientist - Cellular functional assays and organoids** We are seeking an experienced **Senior Scientist to join and shape our cellular assay team based in Munich**, Germany. In this key role, you will be responsible for designing, executing, and interpreting cellular functional assays to validate the activity of small molecules and other therapeutic modalities. Your expertise in cutting - edge methodologies will be crucial in delivering high-quality data, which supports the success of our client projects. Collaborating closely with various departments at Crelux will be essential to drive innovative solutions and accelerate drug discovery programs. **Responsibilities** - Design and conduct **cellular functional assays** for hit characterization, high-throughput screening, and compound profiling. - Lead the development of **state-of-the-art assays**, ensuring innovative and high-quality designs for cellular profiling and characterization of small molecule activity. - Optimize and miniaturize robust screening assays to enhance their efficiency and reliability. - Work closely with cross-functional teams to ensure the successful delivery of client projects, contributing to their overall success. **Required Skills**: - **PhD** (M/F/d) in **Biology**, **Cell Biology**, **Molecular Biology**, **Biochemistry**, or a related scientific field. - **2+ years of hands-on experience in mammalian cell culture**and developing cellular functional assays for - drug development projects. - Expertise in designing advanced cellular assays to assess the activity of small molecules and other - modalities ( e.g., target engagement, signaling, and reporter assays). - Experience with **3D models, primary cells**, and/or **organoids** is a plus. - Experience with CRISPR/Cas9 tools is an advantage - Strong **analytica**l and **problem-solving skills,** with exceptional attention to detail. - Excellent communication skills in **English** (German is a plus). - Self-starter with the ability to work independently, while also thriving in a **collaborative, multidisciplinary** **team environment.** **We offer** A permanent contract (starting as soon as possible) with a competitive salary, modern office workspaces and the opportunity to work in a dynamic and innovative contract research environment. You will have the opportunity to help shape and grow a newly established **cellular assay group**. Access to eGYM Wellpass membership for personalized fitness and wellness plans. **Are you interested?** date) and a current CV to our human resources department:


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