Phd Student

Vor 3 Tagen


Halle Saale, Deutschland Martin-Luther-Universität Halle Wittenberg Vollzeit

**External job advertisement Reg. no. 5-5815/24-D**

**_-Neuausschreibung
- _**

**The Martin Luther University Halle-Wittenberg, Faculty of Natural Sciences I, Institute of Pharmacy, has**

**a vacancy for a temporary position until 31.12.2027 at the earliest possible date as a**

PhD Student (m-w-d)

to be filled as part-time (50 %).

Remuneration will be paid up to pay group E13 TV-L, depending on the tasks assigned and fulfilment of the

personal requirements.

The position is a part of a joint project between the Institute of pharmacy at MLU and computational chem
- istry group at Leibniz Institute of Plant Biochemistry (IPB-Halle). The PhD position will be placed mostly at

the computational chemistry group at IPB Halle (AG Davari).

**Tasks**:

- Preparation of enzyme data from public databases and transcriptomic data
- Development of machine learning (ML) architectures for the prediction of functions and enzyme-substrate

pairs
- In silico enzyme mining
- Prediction of the recombination landscape of enzyme variants by ML models
- Enzyme characterization and preparation of protein mutants
- Possibility to get a doctoral degree is given

**Requirements**:

- Diploma or Master's degree in computational biology, bioinformatics, cheminformatics, computational

(bio)chemistry or biophysics or a comparable field
- Profound knowledge in one of the following areas: Programming language (Python, C/C++), machine learn
- ing and deep learning methods (PyTorch, TensorFlow), knowledge management and databases, computa
- tional biochemistry or biophysics
- Experience in state-of-the-art machine learning methods (deep learning, active learning and reinforcement

learning)
- Previous experience in cheminformatics would be an advantage, but is not a prerequisite.
- Knowledge of biochemical and enzymological methods, e.g. enzyme characterization and protein muta
- tions, is an advantage
- Creative, curious, team-oriented and enthusiastic personality

Applications from severely disabled persons with equal aptitude and qualifications will be given preference.

Women are strongly encouraged to apply. Applicants with a degree that was not obtained at a German higher

education institution must submit a Statement of Comparability for Foreign Higher Education Qualifications

as proof of equivalence.

Published on 07.10.2024 **Page 1 / 2**

CV, copies of diplomas and contact details of two references by 21.10.2024 to Martin Luther University

Application costs will not be reimbursed by Martin Luther University. Application documents will only be returned

Published on 07.10.2024 **Page 2 / 2


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