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Drug Substance Lead for Small Molecules

vor 2 Wochen


Darmstadt, Deutschland Merck KGaA Vollzeit

Work Your Magic with us

Ready to explore, break barriers, and discover more? We know you've got big plans '“ so do we Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

**Your Role**:You, as a Drug Substance-Lead, represent the process chemistry expertise within cross-functional teams and ensure high quality decision making on process development and supply of API. You lead collaborations with our process chemistry partners (within the company and with CDMOs) for our biopharma small molecule projects (NCEs) and antibody-drug-conjugates. Furthermore, you contribute to strategic decisions in the department like out-sourcing models, in-license evaluations (due diligences) and guideline interpretation etc. You report to the head of Drug Substance Development Chemical Sciences within Global Pharmaceutical Development and work in a matrix environment with other functional experts (QC, Formulation).

**Who you are**:

- University degree in organic chemistry preferably with a Ph.D.
- Project related experience in pharmaceutical development & chemical process development for at least 3 to 6 years
- Profound cGMP knowledge
- Experience with high potent drugs and antibody drug conjugates is of advantage
- Broad interdisciplinary experience with interfacing functions in CMC-development
- Excellent communication and negotiation skills Fluent in English

**What we offer**:We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We celebrate all dimensions of diversity and believe that it drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress