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Principal Scientist Clinical Genomics

vor 1 Woche


Frankfurt am Main, Hessen, Deutschland Merck KGaA, Darmstadt, Germany Vollzeit

We have an exciting opportunity for a Scientific Associate Director to join our growing Clinical Genomics team In this role, you will collaborate with a global team of experts to advance implementation of clinical biomarkers and promising technologies. Our team serves as a center of excellence for clinical biomarker measurements at Healthcare R&D, dedicated to improving drug development and patient lives through smart biomarker testing solutions and new technology implementation. We work cross-functionally with research, medical, data science, regulatory, biomarker strategy and CDx experts across our clinical development portfolio. In your role you'll be the technical lead for clinical biomarker assay strategy definition, development, outsourcing and validation under CLIA/CAP and GCLP. Furthermore, you'll contribute to set up of clinical trial related documents and you'll mange clinical biomarker projects within quality, timeline, and budget expectations. This permanent role is based in Darmstadt, Germany but can operate from other European locations. Who you are: PhD/MD or equivalent degreeSpecialist in clinical genomics with excellent hands-on expertise in assay development, validation, implementation, and data QC/interpretation5-10+ years experience in clinical/CDx/translational biomarker development in pharma or equivalentExcellent knowledge of current clinical genomics technology and vendor landscapeUnderstanding of basic regulatory requirements for assaysGood understanding of operational requirements for clinical biomarker implementationScientific background in oncology and/or immunology, expertise in epigenetics is a plusExcellent interpersonal and communication skills, strong team playerDriven by scientific excellence and curiosityStrong publication record demonstrating subject matter expertise