PhD Student – Immunotherapeutic targeting of AML Leukemia-Initiating cells with CAR-T-cells
vor 2 Wochen
We are seeking a highly motivated PhD student to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses and pioneering innovative molecularly-guided therapeutic approaches.
Your role- Acute myeloid leukemia (AML) is a highly aggressive and challenging form of leukemia, especially in children. Despite advancements in cancer treatment, pediatric AML continues to have a poor prognosis and remains difficult to treat, particularly due to the high risk of relapse and upcoming resistance to conventional therapies.
- This PhD project aims to characterize the leukemia-initiating population in pediatric AML with flow cytometry-based enrichment combined with cutting-edge single-cell transcriptomics and proteomics as a basis for the development of targeted CAR-T-cell immunotherapies.
- The anticipated outcomes of this research will not only deepen our understanding of the step-wise progression of pediatric AML, but will also advance the development of new therapies capable of eradicating persistent cancer cells, potentially transforming treatment options for AML.
- Master's degree in life sciences or equivalent
- Passion for discovery of novel therapy approaches and epigenetic mechanisms of gene regulation
- Collaborative spirit & good communication skills
- Experience in basic laboratory techniques (i.e. molecular biology, flow cytometry etc.)
- Proficiency in spoken and written English
- Due to legal regulations, valid proof of measles immunity / measles vaccination is required
- Collective agreement: In addition to an attractive salary based on a collective agreement with an annual special payment, you benefit from long-term security through company pension schemes
- Collaborative spirit: Experience in basic laboratory techniques (i.e. molecular biology, flow cytometry etc.), Proficiency in spoken and written English, Excellent scientific environment & dedicated mentoring, Training in novel cutting-edge techniques to study epigenetic mechanisms in leukemia cells, Collaboration opportunities with national & international world-leading laboratories, Participation in training and qualification programs of the MSNZ and the Goethe University
- Mobility: Free public transport in all Hessen (Free State Ticket Hessen)
- Campus: Our attractive university hospital campus offers a modern cafeteria, various cafes, and opportunities to rest in numerous green spaces. A walk on the riverside of the Main offers relaxation during breaks
- Work-Life-Balance: Part-time employment is possible, we offer childcare in our daycare center (if you have any questions, please contact UKF-Familienservice), child care during holidays
- Health Promotion: Benefit from our attractive health offers. We offer regular online and face-to-face courses on nutrition, relaxation, sports and exercise
- Professional development: Internal and external training for your professional development
- Any questions? Many answers can be found in our FAQs for new employees. If you have any further questions, please do not hesitate to contact us
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Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitPhD Student in Immunotherapeutic Targeting of AML Leukemia-Initiating CellsWe are seeking a highly motivated PhD student to join our Leukemia Research Group at the Department of Pediatrics. The successful candidate will work on a project aimed at characterizing the leukemia-initiating population in pediatric AML using flow cytometry-based enrichment combined...
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Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitPhD Student in Immunotherapeutic Targeting of AML Leukemia-Initiating CellsWe are seeking a highly motivated PhD student to join our Leukemia Research Group at the Department of Pediatrics. The successful candidate will work on a project aimed at characterizing the leukemia-initiating population in pediatric AML using flow cytometry-based enrichment combined...
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Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitPhD Student Opportunity in Immunotherapeutic Targeting of AML Leukemia-Initiating CellsWe are seeking a highly motivated PhD student to join our Leukemia Research Group at the Department of Pediatrics. The successful candidate will contribute to the characterization of the leukemia-initiating population in pediatric AML using flow cytometry-based enrichment...
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Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitPhD Student Opportunity in Immunotherapeutic Targeting of AML Leukemia-Initiating CellsWe are seeking a highly motivated PhD student to join our Leukemia Research Group at the Department of Pediatrics. The successful candidate will contribute to the characterization of the leukemia-initiating population in pediatric AML using flow cytometry-based enrichment...
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Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitAcute Myeloid Leukemia (AML) Research OpportunityWe are seeking a highly motivated PhD student to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses and pioneering...
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Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitAcute Myeloid Leukemia (AML) Research OpportunityWe are seeking a highly motivated PhD student to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses and pioneering...
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Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitPhD Student OpportunityWe are seeking a highly motivated PhD student to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses and pioneering innovative...
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Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitPhD Student OpportunityWe are seeking a highly motivated PhD student to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses and pioneering innovative...
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Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitPhD Student OpportunityWe are seeking a highly motivated PhD student to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses and pioneering innovative...
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Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitPhD Student OpportunityWe are seeking a highly motivated PhD student to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses and pioneering innovative...
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Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitResearch OpportunityWe are seeking a highly motivated PhD student to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology.Project OverviewThe project aims to characterize the leukemia-initiating population in pediatric AML with flow cytometry-based enrichment combined with...
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vor 4 Wochen
Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitResearch OpportunityWe are seeking a highly motivated PhD student to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology.Project OverviewThe project aims to characterize the leukemia-initiating population in pediatric AML with flow cytometry-based enrichment combined with...
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vor 3 Wochen
Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitAcute Myeloid Leukemia (AML) Research OpportunityWe are seeking a highly motivated PhD student to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses and pioneering...
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Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitPhD Student OpportunityWe are seeking a highly motivated PhD student to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses and pioneering innovative...
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Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitPhD Student OpportunityWe are seeking a highly motivated PhD student to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses and pioneering innovative...
-
Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitPhD Student OpportunityWe are seeking a highly motivated PhD student to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses and pioneering innovative...
-
Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitPhD Student OpportunityWe are seeking a highly motivated PhD student to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses and pioneering innovative...
