PhD Student

vor 4 Wochen

Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt Vollzeit
Research Opportunity

We are seeking a highly motivated PhD student to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology.

Project Overview

The project aims to characterize the leukemia-initiating population in pediatric AML with flow cytometry-based enrichment combined with cutting-edge single-cell transcriptomics and proteomics as a basis for the development of targeted CAR-T-cell immunotherapies.

Responsibilities
  • Characterize persistent AML clones during treatment and remission
  • Identify their cell surface profile
  • Design and test CAR constructs
  • Develop preclinical immunotherapy testing
Requirements
  • Master's degree in life sciences or equivalent
  • Passion for discovery of novel therapy approaches and epigenetic mechanisms of gene regulation
  • Collaborative spirit & good communication skills
  • Experience in basic laboratory techniques (i.e. molecular biology, flow cytometry etc.)
  • Proficiency in spoken and written English
What We Offer
  • Attractive salary based on a collective agreement with an annual special payment
  • Long-term security through company pension schemes
  • Excellent scientific environment & dedicated mentoring
  • Training in novel cutting-edge techniques to study epigenetic mechanisms in leukemia cells
  • Collaboration opportunities with national & international world-leading laboratories
  • Participation in training and qualification programs of the MSNZ and the Goethe University
Work-Life-Balance

We offer part-time employment, childcare in our daycare center, and child care during holidays.

Health Promotion

Benefit from our attractive health offers, including regular online and face-to-face courses on nutrition, relaxation, sports, and exercise.

Professional Development

Internal and external training for your professional development.

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