PhD Student
vor 3 Wochen
We are seeking a highly motivated PhD student to join our Leukemia Research Group at the Department of Pediatrics and the Department of Experimental Pediatric Hematology & Oncology. Our joint labs are at the forefront of pediatric leukemia research, focusing on genetic and epigenetic analyses and pioneering innovative molecularly-guided therapeutic approaches.
Project OverviewThe project aims to characterize the leukemia-initiating population in pediatric AML with flow cytometry-based enrichment combined with cutting-edge single-cell transcriptomics and proteomics as a basis for the development of targeted CAR-T-cell immunotherapies. The project will characterize persistent AML clones during treatment and remission, which can give rise to lethal relapse, identify their cell surface profile, and design and test CAR constructs towards the development of preclinical immunotherapy testing.
Requirements- Master's degree in life sciences or equivalent
- Passion for discovery of novel therapy approaches and epigenetic mechanisms of gene regulation
- Collaborative spirit & good communication skills
- Experience in basic laboratory techniques (i.e. molecular biology, flow cytometry etc.)
- Proficiency in spoken and written English
- Collective agreement: attractive salary based on a collective agreement with an annual special payment
- Collaborative spirit: experience in basic laboratory techniques, proficiency in spoken and written English, excellent scientific environment & dedicated mentoring
- Training in novel cutting-edge techniques to study epigenetic mechanisms in leukemia cells
- Collaboration opportunities with national & international world-leading laboratories
- Participation in training and qualification programs of the MSNZ and the Goethe University
We are an equal opportunities employer and welcome applications from all qualified candidates. Women are underrepresented in these positions at the University Hospital Frankfurt. Applications from women are therefore particularly welcome. Disabled applicants are preferred if they have the same personal and professional qualifications.
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