Aktuelle Jobs im Zusammenhang mit PhD Position in Neuroimmunology Research - Bonn, Nordrhein-Westfalen - Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)


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PhD Position in Neuroimmunology Research

vor 3 Monaten


Bonn, Nordrhein-Westfalen, Deutschland Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE) Vollzeit
Position Overview

We are on the lookout for a dedicated and passionate PhD Student (f/m/x) specializing in the field of Neuroimmunology. This role is integral to our research initiatives at the intersection of neuroscience and immunology.

Research Group

The successful candidate will join the 'Translational Neuroimmunology' research group, under the guidance of Dr. Róisín McManus. Our group is based at the DZNE and collaborates closely with the Institute of Innate Immunity at the University Hospital Bonn and the ImmunoSensation2 Cluster of Excellence.

Research Focus

Our primary research aim is to elucidate the role of microglia-mediated neuroinflammation in the advancement of Alzheimer's disease. We investigate how immune signaling and metabolic alterations influence microglial functionality and disease progression.

Your Role

As a PhD student, you will delve into the mechanisms by which dietary habits, particularly a western diet, instigate lipid alterations that activate microglia, leading to neuroinflammation. Your research will utilize a variety of methodologies, including:

  • Animal models of dementia
  • Murine cell culture systems
  • Patient-derived samples

The objective of your PhD will be to uncover the innate immune pathways that mediate neuroinflammatory responses, thereby contributing to our understanding of Alzheimer's disease.

Qualifications

The ideal candidate will possess:

  • A Master's degree in immunology, neuroscience, biology, or a related field
  • Experience in experimental animal research and a background in immunology, neuroscience, or cellular metabolism
  • FELASA accreditation is highly advantageous
  • Practical skills in cell culture (e.g., murine microglia or human iPSC-derived microglia) and biochemical techniques (protein assays, western blot, PCR); familiarity with immunohistochemistry or flow cytometry is a plus
  • Proficiency in English for effective communication, writing, and presentation of scientific findings
  • A keen interest in exploring and innovating new methodologies
  • A collaborative spirit to work within a diverse, interdisciplinary team of international researchers
What We Offer

At our organization, we value:

  • Innovation and International Collaboration: Access to modern laboratory facilities and opportunities for international exchange with colleagues from diverse backgrounds.
  • Work-Life Balance: Flexible working hours, generous vacation policies, and support for family needs.
  • Health and Well-being: Comprehensive health programs and initiatives to promote employee wellness.
  • Professional Development: Tailored training programs and annual reviews to support your career growth.
  • Inclusive Environment: Commitment to equal opportunities and support for individuals with disabilities.

We are excited to welcome a new member to our team who is eager to contribute to groundbreaking research in neuroimmunology.