Postdoc - Aptamer Development Scientist

vor 2 Wochen

Essen, Deutschland Forschungszentrum Jülich Vollzeit

At the Institute of Biological Information Processing - Bioelectronics (IBI-3), our interdisciplinary team of physicists, chemists, biologists, and electrical engineers studies and develops functional assemblies of biological components like aptamer receptors and electronic devices. This collaboration has led to the development of platforms such as electrochemical biosensors.

**Your Job**:
Your tasks will include:

- Design and conducting of SELEX experiments to identify aptamers that bind to specific target molecules of interest. This involves: Design of starting libraries, Optimizing selection conditions, Using various analytical techniques (magnetic beads, capillary electrophoresis, qPCR etc.) to screen, separate, and amplify aptamers, DNA sequencing.
- Characterize aptamer performance using various analytical techniques, such as surface plasmon resonance and fluorescence-based assays.
- Support in the automation of the biosensor fabrication processes and development of standard operating procedures (SOPs) for the SELEX process
- Advance current SELEX processes

**Your Profile**:

- Master degree (or equivalent) and PhD degree in the field of molecular biology, biochemistry, analytical chemistry, or related
- Hands-on experience with aptamer selection (SELEX process) and more specifically with molecular biology techniques such as PCR, qPCR, fluorescence-based assays, protein-DNA/RNA interaction analysis, electrophoresis in gel and capillary, surface plasmon resonance, and next-generation sequencing
- Willingness to familiarize yourself with new methods
- Out-of-the-box thinking and ability to communicate with scientists and technicians from various disciplines
- Well-structured and systematic research approach, as well as statistical and analytical working style
- Experiences in publishing own work

Additional qualifications
- Speaking German is beneficial
- Knowledge of protein production/purification
- Knowledge in bioinformatic analysis and programming is a plus
- Interest in the development of point-of-care biosensor technologies
- Familiarized working with an electronic lab book
- Entrepreneur mindset is a plus

**Our Offer**:
We work on the very latest issues that impact our society and are offering you the chance to actively help in shaping the change We offer ideal conditions for working in a motivated and entrepreneurial team:

- Outstanding scientific and technical infrastructure
- Participation in national and international conferences and workshops
- A large research campus with green spaces, offering the best possible means for networking with colleagues and pursuing sports alongside work (e.g. Institute’s running team)
- Comprehensive training courses and individual opportunities for personal and professional further development
- 30 days of annual leave and provision for days off between public holidays and weekends (e. g. between Christmas and New Year)
- Ideal conditions for balancing work and private life, as well as a family-friendly corporate policy
- Targeted services for international employees, e.g. through our International Advisory Service

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