Scientist Iii, R&d

vor 3 Wochen

Heidelberg, Deutschland Asklepios BioPharmaceutical Vollzeit

Asklepios BioPharmaceutical, Inc. (AskBio) is a leading, clinical-stage gene therapy company founded in 2001 based on the work of adeno-associated virus (AAV) gene therapy visionary and pioneer, Jude Samulski, PhD. Since that time, our commitment to developing life-saving medicines that can potentially cure genetic diseases has never wavered.

At AskBio, we’ve built a foundation of therapeutic programs, AAV manufacturing and a rich portfolio of patented technology. Our therapeutic focus includes neuromuscular, central nervous system, cardiovascular and metabolic diseases with clinical trials underway for Pompe disease, Parkinson’s disease, and congestive heart failure. Our gene therapy platform includes Pro10, an industry-leading proprietary cell line manufacturing process, and an extensive AAV capsid and promoter library.

We became a wholly-owned, independently operated, subsidiary of Bayer AG in late 2020 as a cornerstone of its newly formed Cell & Gene Therapy (CGT) platform. Our global headquarters is in Research Triangle Park, NC. Additionally, we have significant operations in Philadelphia, PA, Columbus, OH, Scotland, France, and Spain.

Our vision: Pioneering science to create transformative molecular medicines.

Our mission: Lead innovative science and drive clinical outcomes to transform people's lives.

Our principles:
- Advance innovative science by pushing boundaries.- Bring transformative therapeutics to patients in need.- Provide an environment for employees to reach their fullest potential.

Our values:
- Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.- Cultivate Collaboration. Strive to be the best teammate, actively listen, openly communicate, and embrace diverse points of view.- Embrace Responsibility. We are humbled by the enormity of our mission. We hold a relentless commitment to advance science and clinical outcomes for our patients, families, and caregivers.- Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.- Act with Uncompromising Integrity. Be honest, transparent, and committed to doing what’s right in every situation. Make clear commitments and follow through.

The Scientist III, R&D at AskBio GmbH will be one of the key members to support the development of rAAV gene therapy with highly complex novel technologies. The scientist has responsibility for analysis of DNA, RNA, and protein expression from tissues and cell lines. Target disease indications include heart, CNS, neuromuscular, liver systemic and liver metabolic diseases innovative approaches to improve AAV capsid development and understanding of underlying AAV biology. New technologies will be used for understanding viral-host interactions. The Scientist actively participate as a member of multifunctional project teams, executing projects from concept to implementation.

**Responsibilities**:

- Lead and perform “hands-on” work in selecting complex AAV-capsid libraries.
- Design experiments and use statistical tools to analyse various data sets and types.
- Develop robust, efficient, scalable strategies for improving AAV capsid developments in collaboration with fellow scientists, external collaborators, and upper management.
- Prepare internally reviewed technical reports, development reports, manuscripts, and deliver internal and external oral presentations.
- Conduct experiments as part of a variety of research and development activities. e.g. small-scale studies, scale up studies, technology transfer and process improvements.
- Actively participate as a member of multifunctional project teams, executing projects from concept to implementation.
- Evaluate and summarize experimental results, develop and test hypotheses to improve understanding AAV capsid selection strategies.

Required Education and Experience
- Master’s degree in Immunology, Biology, Biochemistry, Biotechnology, Virology or a related field
- PhD in a scientific discipline.
- 5-8 years of related experience mainly virology.
- Seen as an internal “go to” for more junior employees who are seeking coaching and direction on highly complex technical issues.
- Expert knowledge in designing, implementing, and troubleshooting experiments.
- Must be able to generate high quality data for presentations and publications.
- Excellent interpersonal skills with the ability to interact effectively with teams, internally and externally.
- Proven ability to work in a fast-paced environment, meet deadlines, & prioritize work on multiple projects. Strong attention to detail with the ability to handle multiple responsibilities simultaneously.
- Acts independently to define new assignments that generates innovative methods and procedures.
- Ability to independently integrate and develop research programs that align with the goals of the company as defined by senior management.
- Contribute to techni

  • Senior Data Scientist

    vor 1 Monat

    Heidelberg, Deutschland Orbis Group Vollzeit

    Titel – Senior Data Scientist Standort – Heidelberg oder Berlin Flexibilität – HybridÜber das Unternehmen Sie sind ein führendes deutsches datengetriebenes Softwareunternehmen, das für seine Kultur bekannt ist und in den drei Regionen, in denen sie in Deutschland tätig sind, einen ausgezeichneten Ruf genießt.Sie bieten vollständig...

  • Senior Computational Scientist

    Vor 5 Tagen

    Heidelberg, Deutschland Embl-Ebi Vollzeit

    Your role We are looking for a senior computational scientist to join the Proteomic Core Facility at EMBL Heidelberg. The Proteomic Core Facility provides scientific support for scientists at EMBL-Heidelberg and its outstations, in the areas of proteomics and structural biology. We offer services in the characterization of proteins and peptides by mass...

  • Data scientist

    vor 1 Monat

    Heidelberg, Baden-Württemberg, Deutschland Universitätsklinikum Heidelberg Vollzeit

    Data scientist (m/f/d)wanted from June 2024 at the Department of Infectious Dieseases and Tropical Medicine.Who we are: The Department of Infectious Disease and Tropical Medicine at Heidelberg University Hospital has a clinical and research mandate. We are embedded in a university campus with a strong interdisciplinary health research focus (incl. the...

  • Senior Computational Scientist

    Vor 4 Tagen

    Heidelberg, Deutschland EMBL Vollzeit

    Your role We are looking for a senior computational scientist to join the Proteomic Core Facility at EMBL Heidelberg. The Proteomic Core Facility provides scientific support for scientists at EMBL-Heidelberg and its outstations, in the areas of proteomics and structural biology. We offer services in the characterization of proteins and peptides by mass...

  • Research Associate Iii

    vor 4 Wochen

    Heidelberg, Deutschland Asklepios BioPharmaceutical Vollzeit

    Asklepios BioPharmaceutical, Inc. (AskBio) is a leading, clinical-stage gene therapy company founded in 2001 based on the work of adeno-associated virus (AAV) gene therapy visionary and pioneer, Jude Samulski, PhD. Since that time, our commitment to developing life-saving medicines that can potentially cure genetic diseases has never wavered. At AskBio,...

  • Research Scientist

    Vor 4 Tagen

    Heidelberg, Baden-Württemberg, Deutschland Reckitt Vollzeit

    We are ReckittHome to the world's best loved and trusted hygiene, health, and nutrition brands. Our purpose defines why we exist: to protect, heal and nurture in the relentless pursuit of a cleaner, healthier world. We are a global team united by this purpose.Join us in our fight to make access to the highest quality hygiene, wellness, and nourishment a...

  • (Junior) Data Scientist

    Vor 5 Tagen

    Heidelberg, Deutschland Lidl Dienstleistung Vollzeit

    Einleitung Wir suchen einen (Junior) Data Scientist (m/w/d), der das Thema Daten & KI bei Lidl Deutschland erfolgreich voranbringt. Du wirst unsere Fachbereiche durch den Einsatz analytischer Methoden dabei unterstützen, operative Prozesse zu verbessern und noch bessere strategische Entscheidungen zu treffen. Mit Deinem Geschäftssinn und Deinem Data...

  • Data Scientist

    vor 2 Wochen

    Heidelberg, Baden-Württemberg, Deutschland Energy Jobline Vollzeit

    Job Descriptiontangro ist führender Software-Anbieter für Inbound-Dokumenten-Management-Lösungen auf SAP-Basis. Wir sind ein mittelständisches, inhabergeführtes Unternehmen mit familiärer Atmosphäre und flachen Strukturen.Unsere Produkte optimieren Geschäftsprozesse: Über 1000 Installationen bei international agierenden Unternehmen und Hidden...

  • Computational Scientist in Part-time

    vor 4 Wochen

    Heidelberg, Deutschland Deutsches Krebsforschungszentrum Vollzeit

    **Position**:Computational Scientist in part-time (65%)** **Department**: Systems Immunology & Single-Cell Biology **Code number**:2024-0082 The German Cancer Research Center is the largest biomedical research institution in Germany. With more than 3,000 employees, we operate an extensive scientific program in the field of cancer research. Our Junior...

  • Research Scientist

    vor 4 Wochen

    Heidelberg, Deutschland Reckitt Vollzeit

    Home to the world's best loved and trusted hygiene, health, and nutrition brands. Our purpose defines why we exist: to protect, heal and nurture in the relentless pursuit of a cleaner, healthier world. We are a global team united by this purpose. Join us in our fight to make access to the highest quality hygiene, wellness, and nourishment a right and not a...

  • Beschäftigte r Im Sekretariatsdienst

    vor 1 Monat

    Heidelberg, Deutschland Pädagogische Hochschule Heidelberg Vollzeit

    Dabei sein für Bildung, Lehre und Wissenschaft Die Pädagogische Hochschule Heidelberg ist eine bildungswissenschaftliche Hochschule mit universitärem Profil. Ihre Kernaufgabe ist die Lehrerinnen - und Lehrerausbildung. Die Forschungsschwerpunkte liegen in den Bildungswissenschaften, den Fachdidaktiken und der Sonderpädagogik. Wissenstransfer,...

  • Research Scientist

    Vor 2 Tagen

    Heidelberg, Deutschland Reckitt Vollzeit

    Research Scientist - Innovation PTS Team (all genders), Hygiene City: Heidelberg We are ReckittHome to the world's best loved and trusted hygiene, health, and nutrition brands. Our purpose defines why we exist: to protect, heal and nurture in the relentless pursuit of a cleaner, healthier world. We are a global team united by this purpose. Join us in our...

  • Msat Scientist

    vor 1 Monat

    Heidelberg, Deutschland AGC Biologics Vollzeit

    **MSAT Scientist (m/w/d) **Biotechnological production of Active Pharmaceutical Ingredient** AGC Biologics, a wholly owned subsidiary of Asahi Glass Company (AGC), is one of the industry leading CDMOs in reliability, technical excellence, and quality — Right and On Time. AGC is a $12B Japanese-owned and publicly traded company based in Tokyo with over...

  • Scientist Product Development Sweet Goods

    vor 1 Monat

    Heidelberg, Deutschland Archer Daniels Midland Company Vollzeit

    Heidelberg Germany Research & Development **Scientist Product Development Sweet Goods & Dairy (m/w/d)** **Vollzeitstellenangebot im CD&D-Team in Heidelberg** ADM setzt die Kraft der Natur frei, um die Lebensqualität zu bereichern. Wir sind ein führendes globales Unternehmen für die Ernährung von Mensch und Tier und bieten Lösungen für die...

  • Scientist R&d Purification

    vor 20 Stunden

    Heidelberg, Deutschland Octapharma Vollzeit

    Job ID: 54376- Location: Heidelberg, DE- Job Level: Professionals- Job Category: Research and Development- Employment Type: Permanent position- Career Level: Octapharma Biopharmaceuticals GmbH a subsidiary of the Octapharma group founded in 1997 is a successful and expanding biotech company in Heidelberg. Our core business is the development of recombinant...

  • Sterilisationsassistent (m/w/d) mit Fachkunde I, II oder III (Voll- oder Teilzeit)

    vor 1 Monat

    Heidelberg, Deutschland Artemed SE Vollzeit

    UnternehmensbeschreibungSeit über 130 Jahren steht das St. Josefskrankenhaus Heidelberg für die Verquickung von Top-Medizin mit Menschlichkeit – unsere zwei Säulen für die hochqualitative medizinische Versorgung der Patientinnen und Patienten in und um Heidelberg. Neben einer hervorragenden Grund-, Regel-, Intensiv sowie notfallmedizinischen Versorgung...

  • Data Scientist

    vor 5 Stunden

    Berlin # Ulm # Heidelberg, DE HMS Analytical Software GmbH Vollzeit

    Unsere über 30-jährige Erfolgsgeschichte im Software Analytics-Bereich zeigt: wir sind hochspezialisierte Experten, wenn es darum geht, datengetriebene Geschäftsmodelle zu schaffen. Durch die Synthese von Data Engineering, Machine Learning und Software Engineering unterstützen wir Unternehmen dabei aus ihren Daten Mehrwerte zu generieren. Unsere über...

  • Senior Data Scientist

    vor 5 Stunden

    Berlin # Ulm # Heidelberg, DE HMS Analytical Software GmbH Vollzeit

    Unsere über 30-jährige Erfolgsgeschichte im Software Analytics-Bereich zeigt: wir sind hochspezialisierte Experten, wenn es darum geht, datengetriebene Geschäftsmodelle zu schaffen. Durch die Synthese von Data Engineering, Machine Learning und Software Engineering unterstützen wir Unternehmen dabei aus ihren Daten Mehrwerte zu generieren. Unsere über...

  • MSAT Scientist

    vor 1 Monat

    Heidelberg, Deutschland AGC Biologics Vollzeit

    MSAT Scientist (m/w/d) Biotechnological production of Active Pharmaceutical Ingredient  With facilities in the USA, Japan, Denmark, Italy and Germany, AGC Biologics provides fully integrated biopharmaceutical development and manufacturing solutions to clients globally. The Company has proven expertise in delivering custom solutions for the scale-up...

  • Arzt:Ärztin / Wissenschaftler:in / Physician Scientist (m/w/d)

    vor 1 Monat

    Heidelberg, Deutschland DKFZ Vollzeit

    Ihre Aufgaben: Betreuung und wissenschaftlich-strategische Weiterentwicklung von Präzisionsonkologie-Studien Mitgestaltung eines wöchentlichen molekularen Tumorboards (klinische und wissenschaftliche Interpretation von molekularen Datensätzen innerhalb eines interdisziplinären Teams von Kliniker:innen, Molekularbiolog:innen und...