Research Associate Iii

vor 3 Wochen

Heidelberg, Deutschland Asklepios BioPharmaceutical Vollzeit

Asklepios BioPharmaceutical, Inc. (AskBio) is a leading, clinical-stage gene therapy company founded in 2001 based on the work of adeno-associated virus (AAV) gene therapy visionary and pioneer, Jude Samulski, PhD. Since that time, our commitment to developing life-saving medicines that can potentially cure genetic diseases has never wavered.

At AskBio, we’ve built a foundation of therapeutic programs, AAV manufacturing and a rich portfolio of patented technology. Our therapeutic focus includes neuromuscular, central nervous system, cardiovascular and metabolic diseases with clinical trials underway for Pompe disease, Parkinson’s disease, and congestive heart failure. Our gene therapy platform includes Pro10, an industry-leading proprietary cell line manufacturing process, and an extensive AAV capsid and promoter library.

We became a wholly-owned, independently operated, subsidiary of Bayer AG in late 2020 as a cornerstone of its newly formed Cell & Gene Therapy (CGT) platform. Our global headquarters is in Research Triangle Park, NC. Additionally, we have significant operations in Philadelphia, PA, Columbus, OH, Scotland, France, and Spain.

Our vision: Pioneering science to create transformative molecular medicines.

Our mission: Lead innovative science and drive clinical outcomes to transform people's lives.

Our principles:
- Advance innovative science by pushing boundaries.- Bring transformative therapeutics to patients in need.- Provide an environment for employees to reach their fullest potential.

Our values:
- Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.- Cultivate Collaboration. Strive to be the best teammate, actively listen, openly communicate, and embrace diverse points of view.- Embrace Responsibility. We are humbled by the enormity of our mission. We hold a relentless commitment to advance science and clinical outcomes for our patients, families, and caregivers.- Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.- Act with Uncompromising Integrity. Be honest, transparent, and committed to doing what’s right in every situation. Make clear commitments and follow through.

The Research Associate III, R&D at AskBio GmbH will be one of the key laboratory members who will have an opportunity to learn and contribute to the build-out of a new laboratory and preparing and analyzing

**Responsibilities**:

- Cultivation of culture cell lines and primary cells.
- Small-scale AAV productions, virus characterization and labeling.
- Processing of _in vitro_ samples for function and imaging studies.
- Establishment and optimization of culture conditions to reach reproducible formation and maintenance of organoid systems for relevant therapeutic targets.
- Execute transduction assays.
- Maintain entries in Benchling, recording details of performed experiments according to good documentation practices.
- Maintain inventories and/or place orders of reagents and materials needed for the assigned projects for timely execution of related lab work.
- Assist with the maintenance, calibration and management of laboratory equipment.
- Perform data analysis and interpret the results.
- Contribute to drafting the reports and presentations for technical discussions and/ or investigations with internal and external stakeholders.

Required Education and Experience
- Bachelor’s degree required in Immunology, Biology, Biochemistry, Biotechnology, Virology or a related field and 5+ years of relevant experience or; Masters in a relevant field and 3+ year of experience.
- Must possess basic lab skills such as adhering to biosafety and chemical use guidelines (training provided) and making reagents at desired dilutions or concentrations.
- Demonstrated experience in the aseptic handling of cell cultures or in the processing of clinical samples is required.
- Experience with mammalian cell culture and processing/handling of primary cells.
- Possess office skills using a PC and working with MS office tools (Word, Excel and PowerPoint).
- Self-motivated, organized, individual capable of working independently as well as a team contributor.
- Strong oral and written communication skills.
- Excellent interpersonal skills with the ability to interact effectively with teams, internally and externally.
- ._
- Agencies: Please do not contact any employee at AskBio about this requisition. Any resume submitted by a recruitment agency to any employee at AskBio, through any medium, will be deemed the sole property of AskBio _unless

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