Research Associate

vor 7 Monaten

Hannover, Deutschland Evotec Vollzeit

Evotec is a leader in the discovery and development of novel pharmaceuticals with operational sites in Europe and the US. The company has built substantial drug discovery expertise and an industrialized platform that can drive new innovative drugs into the clinic. In addition, Evotec has built a deep internal knowledge-base for the treatment of diseases related to infectious diseases, neuroscience, pain, oncology, inflammation, and metabolic diseases. Leveraging these skills and expertise, the company intends to develop best-in-class differentiated therapeutics and deliver superior science-driven discovery alliances with pharmaceutical and biotechnology companies.

New medicines for treating tuberculosis are urgently needed, particularly in developing countries. The spread of antibiotic-resistant M. tuberculosis (Mtb) strains results in a critical shortage of effective medications for treatment. In order to counteract this trend, Evotec collaborates with the Helmholtz Centre for Infection Research (HZI) in Braunschweig and its Saarbrücken-based branch, the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS). The Bill & Melinda Gates Foundation is funding this collaboration in which Evotec is participating as a partner of HIPS. Evotec is contributing additional investment to establish novel technologies for identifying novel chemical scaffolds with Mtb activity.

Research Associate (f/m/d) - Evotec GmbH, located at Helmholtz Institute for Pharmaceutical Research Saarland Saarbrücken

Full-time and non-permanent (24 Month)

Discovery of Antibiotics with Mtb activity

Your key responsibilities
- Discovery of novel natural products with activity against Mycobacterium tuberculosis using s high throughput droplet microfluidics screen
- Generation of new M. tuberculosis screening strains in collaboration with our TB team in Lyon
- Fermentation and purification of natural products
- Work collaboratively with colleagues at Evotec sites from Lyon as well as with our HIPS/Evotec team in Saarbrücken
- Meet high standards for quality and turn-around time of bacteriological tests
- Deliver accurate and timely data to profile novel compounds
- Plan, analyze, and record experiments and present data at project meetings

Your qualifications
- A PhDs in pharmaceutical sciences, microbiology, molecular microbiology or bacteriology with a strong interest in natural products drug discovery
- Experience in in natural products discovery, in microbiology/bacteriology as well as in performing biochemical assays using multiple technologies
- Experience with molecular biology techniques is a plus
- Experience in working at high-throughput scales, including the setting up and running of automated workflows is a requirement
- Good written and spoken communication skills in English is required, German is a plus
- Highly self-motivated as the ability to work well in a cross-functional and cross-site teams

**Offer**:

- A position within a vigorous and exciting professional environment promoted by an open culture and a spirit of community
- A diverse, international workforce with a dynamic working environment that fosters creativity, innovations and teamwork
- Capital-forming benefits, holiday pay and annual bonus payment depending on performance

The position is available at Evotec. Administrative affiliation to the site in Göttingen and relation to the team of the infectious disease unit in Lyon (France) is a given. The work place is at the HIPS in Saarbrücken.

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