Postdoc F/m/d

vor 3 Monaten

Düsseldorf, Deutschland Max-Planck-Institut für Eisenforschung GmbH Vollzeit

The mission of the Max-Planck-Institute for Sustainable Materials (MPISusMat) is to understand and design materials down to atomic and scales. In this spirit, we conduct basic research on structural and functional materials, mostly metallic alloys, embracing synthesis and processing, characterization and properties, as well as their response in engineering components exposed to real environmental conditions. However, due to their unique hierarchical structure and excellent mechanical properties, biological materials are of great interest to better understand their properties and use this knowledge to design better engineering materials. We work interdisciplinary, with intense mutual stimulation among experimentalists and theoreticians as well as among different groups and departments.

PostDoc f/m/d - Understanding biomineralization mechanisms by using atom probe tomography (APT)

Your tasks

Biominerals are hierarchically structured and exhibit remarkable properties due to their unique combination of organic and inorganic components. Hydroxyapatite (HAP) is the major mineral phase in bone and teeth (enamel and dentine), providing high stiffness, strength and wear resistance and forming a hierarchical composite with inorganic component (collagen and other proteins). The different processes of formation of both components is named biomineralization. Despite advances in deciphering the organization and structure of the HAP nanocrystals, the presence of substitutional trace elements at their interface is still not yet fully understood e.g. the chemical composition and proteins binding. This leaves many fundamental questions about mineralization processes unanswered, partly due to the challenge of simultaneously characterizing the three-dimensional (3D) structure and chemical composition at the nanometer scale of these materials.

Atom probe tomography (APT)provides 3D nanoscale compositional mapping with high chemical sensitivity. This technique could solve her questions exposed above. While APT is well established for analyzing metallic materials, in recent years, it has been extended to biominerals research, although there remain challenges; the heterogeneous structure of the inorganic and organic domains limits yield and complexifies the data. Preliminary work by our group paves the way for systematic analyses of biomaterials and will accelerate new insights into biomineralization processes.

We are looking for a PostDoc to further establish the frontiers of biomineral research using APT and to answer biological questions related to biomineralization.

Your tasks will be:

- Preparation of specimens using metallographic (grinding, polishing) and micromechanical tools for microstructural investigations
- Performing microstructural characterization on different length scales using electron microscopy techniques such as SEM/FIB (tomography) and TEM combined with spectroscopy methods (e.g. EDS, EELS)
- Measurement of mechanical properties
- Sample preparation using focused ion beam milling (FIB) for APT analysis
- The focus is on high resolution structural and chemical analysis using APT
- Interpretation of results from a biological perspective and combine results from different length scales and methods
- Establish, manage and coordinate collaboration between MPIE and partner Institutes
- Write funding proposals to national organization (DFG) or European consortiums
- Publication of scientific results in international journals and presentation of scientific results at conferences and meetings.

**Profile**:
Doctoral degree in structural biology/ _Palaeontology,_ materials science or related

Strong background in biomineralization and structural characterization, with a very good understanding of the principles of microstructural evolution

Knowledge and experience should be either in understanding biomineralization mechanisms, or experimental work related to SEM and FIB preparation and TEM.

Experience and knowledge of atom probe tomography (APT) would be desirable but is not essential.

Good English skills are mandatory. MPISusMat is an international workplace, the daily and professional language is English.

Interest to acquire new skills related to microscopy techniques or biomineral side

What we offer

The MPISusMat offers an exciting and stimulating research environment with high-level experts and access besides APT to state-of-the-art research equipment for material characterization.

You will be part of an international and collaborative research team in the field of atom probe tomography at the Max-Planck Institute.

You will be directly supervised by Prof. Baptiste Gault and Dr. Tim SchwarzThe salary is based on TVöD 13, depending on qualifications. The contract will be temporary for 2 years with options for extension.

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