Scientist (M/F/d) Cell Line Development
vor 3 Wochen
Job ID: 54247- Location: Heidelberg, DE- Job Level: Professionals- Job Category: Research and Development- Employment Type: Permanent position- Career Level:
Octapharma Biopharmaceuticals GmbH a subsidiary of the Octapharma group founded in 1997 is a successful and expanding biotech company in Heidelberg. Our core business is the development of recombinant proteins produced in human cell lines for therapeutic use in humans. We strive for effective treatments with an improved tolerability and convenience for the patient.
**We are looking for**:
A skilled and motivated Scientist (M/F/d) to join our R&D CLD team, dedicated to cell line development for production of therapeutics in the area of hematology and immunology.
**Your Role and Responsibilities**:
- Design cell line development projects and perform key activities associated with production cell line development including transfection, selection, single cell cloning, high throughput screening and characterization of clonal cell lines
- Plan, execute and analyze cell line development campaigns for generating production clones to be used for preclinical and clinical manufacturing of therapeutic proteins
- Further develop our clone generation platforms, based on HEK 293-F and CHO cells, including expression vector development and clone screening workflows, by implementing innovative technologies
- Develop and optimize bioprocesses on the ambr15 micro bioreactor system
- Establish molecule-specific expression strategies by engineering cell lines towards improved protein production employing state-of-the-art gene editing technologies
- Provide advice and expertise for fellow Research Associate colleagues on daily basis
- Initiate scientific discussions in the team and conduct literature research for implementing recent scientific and technological developments in our workflows
- Present scientific concepts and data as well as report on project progress in internal and external meetings
***Your Qualifications and Education**:
- You hold a PhD degree in biochemistry, biotechnology, biology or related discipline
- You have a strong background in molecular and cell biology as well as a profound documented record of experience with the development of recombinant mammalian cell lines
- Experience with automated liquid handling systems and ambr15 micro bioreactors is a plus
- You possess very good communication skills as well as scientific writing and documentation competencies
- You value and live to a high degree of responsibility, reliability, autonomy, and team orientated mindset
You are creative and eager to solve scientific challenges while coordinating your efforts with your team colleagues. You make space for in-depth analysis of your results to perform the experiment that will make the difference. Your open-minded point of view as well as scientific excellence will help to foster the welcoming and professional working atmosphere in our group. If this is you, do not hesitate to apply
**We offer**:
- Permanent position in a dynamically growing company
- Work in a collegial and scientifically inspiring atmosphere
- Variability of tasks and opportunities to take over responsibility
- Staying informed about latest trends by attending scientific conferences and workshops
- Company learning hub with education, self-improvement, and training opportunities
- Laboratories with modern, state-of-the-art equipment
- 30 days of paid annual leave
- Job-Ticket, underground parking for your car or bicycle
- In-house canteen, company subsidized
***Application**:
**Contact person**:
Dorothee Schaupp - Human Resources
Tel: +49 (0)6221 - 1852 546
**Working at Octapharma**:
Whether your interests lie in the field of research and development, production, marketing, sales, finance or engineering, there are many career opportunities at Octapharma
We are the world's largest family-owned plasma company and entirely European. In the spirit of our founder Wolfgang Marguerre, we do not pursue short-term profit goals, but have future generations in mind. Our vision: we are passionate about developing new healthcare solutions that improve lives. We own 6 modern production facilities in Austria, France, Germany, Sweden and Mexico. The Marguerre family continues to play an essential role in the company's day-to-day operations.
Octapharma wants to offer its employees a working environment that challenges them as much as it enriches them. Since its foundation in 1983, the company has grown steadily and today we employ almost 10,000 people.
**About Octapharma**:
Headquartered in Lachen, Switzerland, Octapharma is one of the largest human protein manufacturers in the world, developing and producing human proteins from human plasma and human cell lines.
Octapharma employs around 10,000 people worldwide to support the treatment of patients in 118 countries with products across three therapeutic areas: Hematology, Immunotherapy and Critical Care.
Octapharma has seven R&D sites and
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