(Senior) Technical Assistant

vor 4 Monaten

Planegg, Deutschland Ascend Gene & Cell Therapies Vollzeit

**Title**: (Senior) Technical Assistant - Analytical Development, Cell Biology (m / w / d)

**Reporting to**: Team Leader Analytical Development, Cell Biology

**Location**: Munich, Germany

**About Ascend**:
Ascend is a new model for gene & cell therapy design, development, and manufacturing. We partner with ambitious biotechnology teams to embed scalable manufacturing in their operations from the beginning. We support manufacturing and process development projects from design through to clinical and commercial scale.

To strengthen our analytical development department, we are looking for a full-time position at our Munich site at the earliest possible date.

**Why we’re different**:
We’re building a place for people inspired by the possibilities of biological engineering for gene & cell therapy technologies. We want to lift up a new generation of experts and breakthrough start-ups. That's why the Ascend model includes the opportunity of cross-functional training to enhance professional development and continually seed fresh ideas.

**Requirements**:
**Main Responsibilities**:

- Collaboration in the development and qualification of cell-based assays to determine the biological activity and safety of viral vectors
- Execution of all cell culture measures to maintain routine cell culture as well as to perform various assay formats
- Collaboration in the development and qualification of various assay read outs (ELISA, enzymatic activity assays, TCID50) including statistical analysis
- Creation of SOP-like work instructions and development reports in R&D
- Working with organisms of risk groups 1 and 2
- Collaboration in the establishment of a QC laboratory, validation of cell-based assays and writing of SOP instructions under GMP
- Tasks for general laboratory organization and maintenance of laboratory operations in R&D and QC

**What you’ll bring**:

- CTA, BTA or MTA with at least 5 years work experience
- Experience in cell biological techniques (cultivation of adherent and suspension cells under aseptic conditions, plasmid transfection and viral transduction / infection, cell culture assays in microtiter plate format)
- Experience in molecular and protein biochemical methods: qPCR, ddPCR, ELISA, activity assays (kinetic and endpoint)
- Well-structured, precise working skills and very high demands on the quality of work
- Open communication and strong team spirit
- Motivated, curious and enjoying challenging activities
- Computer skills (especially Excel) and interest in statistics
- Good knowledge of German and English

**Additional skills**
- Previous knowledge in the field of virology, especially with AAV and with work under biological safety level 2
- Experience in the GMP environment

**Benefits**
- Sodexo staff discounts
- 30 days holiday
- Performance based Bonus
- Standard pension
- More to come as we grow

**What we look for**:

- **Motivational team member**: understands that teamwork comes first, sees the bigger picture and the value of succeeding for all
- **Accountable leader**: is first to stand up for team and product, and take responsibility to drive results
- **Flexible problem-solver**: is solution-orientated and approaches challenges with creativity and curiosity
- **Focused executor**: is passionate about quality work, delivers on time, is proactive and driven to succeed
- **Straightforward communicator**: is open, honest, admits mistakes, listens, and develops with others

Does this sound like the sort of team you’d like to be a part of? Interested in growing in an interdisciplinary creative space and pursuing your passion projects? Please get in touch

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