Scientist (M/F/d) Developability and Formulation

vor 2 Monaten

Heidelberg, Deutschland Octapharma Vollzeit

Job ID: 55355- Location: Heidelberg, DE- Job Level: Professionals- Job Category: Research and Development- Employment Type: Permanent position- Career Level:
Octapharma Biopharmaceuticals GmbH a subsidiary of the Octapharma group founded in 1997 is a successful and expanding biotech company in Heidelberg. Our core business is the development of recombinant proteins produced in human cell lines for therapeutic use in humans. We strive for effective treatments with an improved tolerability and convenience for the patient.

**We are looking for**:
This permanent position is available at the next possible date at our site in Heidelberg.

**Responsibilities**:

- Develop, implement and continuously re-evaluate high-throughput, cutting-edge developability screening strategies for a wide range of biomolecules
- Investigate protein structure-biophysical property relationships and establish correlations between biophysical properties and in silico predictions
- Design, coordinate and execute formulation studies in accordance with QbD and DoE strategies
- Plan and conduct complex experiments on robotic high-throughput platforms, statistically analyze large datasets, document and interpret results
- Present and discuss data and scientific literature in internal and external meetings
- Scientific supervision of student assistants and research associates
- Keep up with the latest developments in the field and integrate the information into the project

***Your profile**:

- PhD degree in protein biochemistry, structural biology, biophysics or equivalent, ideally combined with 2 years of relevant industry experience or M.Sc. plus 5 years of relevant industry experience
- Deep understanding of protein structures, biophysical properties, and their relationship
- Hands-on experience in methods and techniques specific to formulation development such as DLS/SLS, SEC, HIC, icIEF, nanoDSF, DSC, Light Obscuration and Flow Imaging Microscopy
- Experience in aspects of protein formulation, selection of suitable excipients, and freeze-drying process development is of advantage
- Strong organizational and outstanding problem-solving skills, critical and independent thinking, ability to multi-task, and attention to detail
- Expertise in the implementation of assays and workflows on liquid handling platforms is a plus
- First experience with DoE, QbD and programming languages (e.g. Python) is a benefit

***We offer**:

- Permanent position in a dynamically growing company
- Work in a welcoming and scientifically inspiring atmosphere
- Have a wide range of tasks in a cooperative setting, flexibility and personal responsibility
- Stay informed about recent trends by attending scientific conferences and workshops
- Further education, self-improvement and training opportunities
- Work in modern, state-of-the art equipped labs
- Flexible working hours, 30 days of paid annual leave
- Job-Ticket, underground parking for your car or bicycle

***Application**:
**Contact person**:
Dorothee Schaupp - Human Resources
Tel: +49 (0)6221 - 1852 546

**Working at Octapharma**:
Whether your interests lie in the field of research and development, production, marketing, sales, finance or engineering, there are many career opportunities at Octapharma

We are the world's largest family-owned plasma company and entirely European. In the spirit of our founder Wolfgang Marguerre, we do not pursue short-term profit goals, but have future generations in mind. Our vision: we are passionate about developing new healthcare solutions that improve lives. We own 6 modern production facilities in Austria, France, Germany, Sweden and Mexico. The Marguerre family continues to play an essential role in the company's day-to-day operations.

Octapharma wants to offer its employees a working environment that challenges them as much as it enriches them. Since its foundation in 1983, the company has grown steadily and today we employ almost 10,000 people.

**About Octapharma**:
Headquartered in Lachen, Switzerland, Octapharma is one of the largest human protein manufacturers in the world, developing and producing human proteins from human plasma and human cell lines.

Octapharma employs more than 11,000 people worldwide to support the treatment of patients in 118 countries with products across three therapeutic areas: Hematology, Immunotherapy and Critical Care.

Octapharma has seven R&D sites and five state-of-the-art manufacturing facilities in Austria, France, Germany and Sweden, and operates more than 190 plasma donation centers across Europe and the US.

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