Postdoc – Molecular and bioinformatic-based identification of optimized enzymes for biotechnological applications
vor 6 Monaten
Your Job:
Analyzing RNAseq data with respect to the identification and functional annotation of genes involved in, for example, cell wall degradation, carbon flux etc.Screening metagenomic and genomic data using deep learning methods in order to identify degrading enzymes from different data resources
Using Hidden Markov Models and similar tools as well as machine learning for the identification of novel and better enzyme variants from a large proteome compendium
Generating structural models of enzymes and using machine learning methods to predict their enzymatic function and characterize their molecular recognition properties
Using machine learning methods and simulation techniques to understand environmental effects on the enzymes and improving their stability and activity
Publishing the scientific results in international journals and traveling to national and international conferences
(Co)-supervising PhD students
Your Profile:
University degree (Master) and doctorate in bioinformatics, computer science, data science, biophysics, or life science-related fields with a proven track record in bioinformatics, biophysics, data analysis, and simulation sciencesVery good practical experience in molecular biology, Next Generation Sequencing, and structural biology
Extensive experience in analyzing large datasets (especially genomics, transcriptomics, metagenomics, enzyme data, and structural data)
Experience with the application of machine learning methods for data analysis and interpretation
Knowledge in programming languages ( Java, Rust, C/C++, Python) and statistical analysis using R/BioConductor/python
Proven scientific communication skills in the form of scientific publications or equivalent
Willingness to complement and collaborate with existing research units at the research center
Excellent English language skills, both written and spoken are a requirement due to the international nature of the institute and collaborations
Our Offer:
We work on the very latest issues that impact our society and are offering you the chance to actively help in shaping the change We support you in your work with:
Outstanding scientific and technical infrastructure
Creative and international team that conducts research at the frontiers of science
The Forschungszentrum Jülich is one of the largest research centres in Europe with excellent scientific equipment, including the fastest supercomputer in Europe, is located on a green campus, and near the cultural centres of Cologne, Düsseldorf and Bonn
A highly motivated group and an international and interdisciplinary working environment in one of the largest research institutions in Europe
The possibility to develop your own research program in line with the institute and center strategy
Flexible working hours in a full-time position with the option of slightly reduced working hours
30 days of annual leave and provision for days off between public holidays and weekends ( between Christmas and New Year)
Targeted services for international employees, through our International Advisory Service
We offer you an exciting and varied role in an international and interdisciplinary working environment. The position is for a fixed term of 2,5 years, with possible long-term prospects. Salary and social benefits will conform to the provisions of the Collective Agreement for the Public Service (TVöD-Bund), pay group EG 13, depending on the applicant’s qualifications and the precise nature of the tasks assigned to them.
In addition to exciting tasks and a collaborative working atmosphere at Jülich, we have a lot more to offer:
We welcome applications from people with diverse backgrounds, in terms of age, gender, disability, sexual orientation / identity, and social, ethnic and religious origin. A diverse and inclusive working environment with equal opportunities in which everyone can realize their potential is important to us.
We look forward to receiving your application by
Questions about the offer?
Please feel free to contact us via our contact form.
Please note that for technical reasons we cannot accept applications by e-mail.
You can find helpful information on the application and selection process here. You can also find answers to frequently asked questions in our FAQs.
-
Jülich, Deutschland Forschungszentrum Jülich VollzeitYour Job: Building on in-house fabricated devices, we have recently demonstrated the ability to shuttle electrons between gate defined quantum dots in Si/SiGe over micron-scale distances using only four different AC-voltages, independent of the distance covered . Theoretical consideration indicate good prospects for maintaining spin-coherence of the...
-
Postdoc - Detection of Solar and Volcanic
vor 2 Monaten
Jülich, Deutschland Forschungszentrum Jülich VollzeitThe Institute of Climate and Energy Systems - Stratosphere (ICE-4) develops instruments, conducts global observations, and runs chemistry-climate models to study the stratosphere’s role in the climate system. Our mission is to enhance climate and weather predictability by examining atmospheric processes driving circulation, composition variability and...
-
PhD Position
vor 6 Monaten
Jülich, Deutschland Forschungszentrum Jülich VollzeitYour Job: This EU-funded project is part of the international training network Bio-GENTLE, which will connect professionals of various backgrounds from academics and industry. A unique interdisciplinary approach combines fundamental analysis, experimentation, and mathematical modeling to create a flexible bio-separation platform. A cohort of 12 doctoral...
-
Jülich, Deutschland Forschungszentrum Jülich VollzeitYour Job: The contribution of PGI-2 is scientific and toward further development of precise model to predict the response of superconducting quantum processors, aiming at constructing new schemes to better qubits and gates. The PGI-2 team, coordinated by Dr. Ansari , is renowned globally for its expertise in accurately modeling such processors. The group...
-
Jülich, Deutschland Forschungszentrum Jülich VollzeitYour Job: We invite applications for a 1-year Postdoctoral Researcher position, with the possibility of extension based on performance, within a leading EU-funded project aimed at accelerating the adoption and digital transformation in the renewable energy sector. This initiative seeks to harness the latest advancements in cloud computing solutions, data...
-
Jülich, Deutschland Forschungszentrum Jülich VollzeitYour Job: At IEK-9, we are developing exciting interdisciplinary methods to investigate the key mechanisms in batteries and electrolysis using pulsed NMR. By understanding the spin states that have to be experimentally prepared we are tailoring magnetic pulses to push the limits of NMR in operando experiments, probing for example interfaces or membranes....
-
Master Thesis: Spatial and Mechanosensitive
vor 2 Monaten
Jülich, Deutschland Forschungszentrum Jülich Vollzeit**Your Job**: The project concentrates on the signal processing mechanisms between cells, their protective basement membrane (BM) migration barrier and the surrounding extracellular matrix (ECM). It hypothesizes a fingerprint-signaling network of the oncoprotein HRas that forces BM transmigration of breast cancer cells. Your study will consist of assessing...
-
Jülich, Deutschland Forschungszentrum Jülich VollzeitYour Job: This position focuses on developing, operating, and characterizing superconducting quantum devices. Your tasks in detail are: Development of novel methods for experimentation, fabrication, and characterization Develop gate implementations, benchmarking and algorithms Work on the interdisciplinary challenges in systems engineering ...
-
Phd Position
vor 3 Stunden
Jülich, Deutschland Forschungszentrum Jülich VollzeitAs a leading research institution for plant sciences and microbial biotechnology the Institute of Bio - and Geosciences (IBG) at the Forschungszentrum Jülich focuses on molecular and applied biosciences in plants and microbes. The project will develop innovative aspects of biologically sustainable plant biocontroll agents, and builds on existing basic...
-
Senior Software Engineer
vor 4 Wochen
Jülich, Nordrhein-Westfalen, Deutschland Forschungszentrum Jülich VollzeitJob Description: We are seeking a skilled Software Engineer to join our team. The successful candidate will be responsible for the development and maintenance of high-quality software applications. Key responsibilities include designing and implementing complex software solutions, collaborating with cross-functional teams, and ensuring timely delivery of...
-
Jülich, Deutschland Forschungszentrum Jülich VollzeitYour Job: At IEK-9, we are developing exciting interdisciplinary methods to investigate the key mechanisms in batteries and electrolysis using pulsed NMR. By understanding the spin states that have to be experimentally prepared, we are tailoring magnetic pulses to push the limits of NMR in operando experiments, probing for example interfaces or...
-
Phd Position
vor 3 Stunden
Jülich, Deutschland Forschungszentrum Jülich Vollzeit**Your Job**: - Solution-processed fabrication of perovskite films, layer stacks and solar cells - Deposition of insulating layers at the device interfaces using atomic layer deposition (ALD) - Optoelectronic measurements of insulator-based perovskite devices in the time and frequency domain - Transient photoluminescence measurements of perovskite films,...
-
Jülich, Deutschland Forschungszentrum Jülich VollzeitYour Job: Characterize the diurnal and seasonal dynamics of changes in canopy structure under agrivoltaics Deliver 3-dimensional data on plant canopies using commercial and experimental plant phenotyping methods and develop approaches to extract quantitative plant traits from 3-D point clouds Understand the effects of dynamically altered light...
-
Master Thesis
vor 6 Monaten
Jülich, Deutschland Forschungszentrum Jülich VollzeitYour Job: Quantifying the activity of enzymes operating within the large-scale biochemical network is a fundamental challenge in Systems Bio(tech)nology. Here, the unknown parameters must be inferred from models that are incomplete and data that involve errors. For such challenges, Bayesian analysis using Markov Chain Monte Carlo (MCMC) has become the...
-
Master Thesis
vor 5 Monaten
Jülich, Deutschland Forschungszentrum Jülich VollzeitYour Job: Within the scope of various national and international projects, electrochemical processes in solid oxide fuel cells as well as electrolysis cells are investigated. We specifically are looking for a master student with experience in the field of development of thin film electrodes for SOFC / SOEC. Additionally, depending on your field of...
-
PhD Position
vor 6 Monaten
Jülich, Deutschland Forschungszentrum Jülich VollzeitYour Job: Characterization and optimization of a lab-based GC-HID-ECD instrument to measure H2, CH4, N2O and SF6 Construction and characterization of an AirCore to sample air masses without disturbance of the target trace gases Conducting regular balloon launches with AirCores in Jülich and analysis of collected air samples with the GC-HID-ECD...
-
Master Thesis or Internship
vor 6 Monaten
Jülich, Deutschland Forschungszentrum Jülich VollzeitYour Job: Review of (classical) partitioning algorithms, spectral methods based on Network Modularity Identification of use cases for graph partitioning in power systems related studies, for State Estimation Develope new or tailor existing QUBO (Quadratic Unconstrianed Binary Optimization) formulations for graph partitioning objecitves to the use...
-
Quantum Computing Researcher
vor 4 Wochen
Jülich, Nordrhein-Westfalen, Deutschland Forschungszentrum Jülich VollzeitAbout the Project:The PGI-2 team, led by Dr. Ansari, is renowned globally for its expertise in accurately modeling superconducting quantum processors. The group specializes in integrating machine learning techniques with circuit QED theory to identify optimal regimes for hardware control and development. Our objective is to refine the model for greater...
-
Phd Position
Vor 4 Tagen
Jülich, Deutschland Forschungszentrum Jülich VollzeitAre you passionate about science? Would you like to contribute to research on breeding crops resilient to climate change? Come to work with us at the Institute of Bio **Your Job**: - Responsible for characterizing root and shoot architecture of selected rye genotypes using imaging-based phenotyping platforms, - Derive, in cooperation with other scientists,...
-
Phd Position
vor 3 Stunden
Jülich, Deutschland Forschungszentrum Jülich Vollzeit**Your Job**: - Optoelectronic measurements of insulator-based perovskite devices in the time and frequency domain - Transient photoluminescence measurements of perovskite films, layer stacks and insulator-based devices - Ultraviolet photoelectron spectroscopy (UPS) measurements to determine perovskite/transport layer band offsets - Data analysis using a...