Postdoc – Molecular and bioinformatic-based identification of optimized enzymes for biotechnological applications

vor 6 Monaten


Jülich, Deutschland Forschungszentrum Jülich Vollzeit

Your Job:

Analyzing RNAseq data with respect to the identification and functional annotation of genes involved in, for example, cell wall degradation, carbon flux etc.
Screening metagenomic and genomic data using deep learning methods in order to identify degrading enzymes from different data resources
Using Hidden Markov Models and similar tools as well as machine learning for the identification of novel and better enzyme variants from a large proteome compendium
Generating structural models of enzymes and using machine learning methods to predict their enzymatic function and characterize their molecular recognition properties
Using machine learning methods and simulation techniques to understand environmental effects on the enzymes and improving their stability and activity
Publishing the scientific results in international journals and traveling to national and international conferences
(Co)-supervising PhD students

Your Profile:

University degree (Master) and doctorate in bioinformatics, computer science, data science, biophysics, or life science-related fields with a proven track record in bioinformatics, biophysics, data analysis, and simulation sciences
Very good practical experience in molecular biology, Next Generation Sequencing, and structural biology
Extensive experience in analyzing large datasets (especially genomics, transcriptomics, metagenomics, enzyme data, and structural data)
Experience with the application of machine learning methods for data analysis and interpretation
Knowledge in programming languages ( Java, Rust, C/C++, Python) and statistical analysis using R/BioConductor/python
Proven scientific communication skills in the form of scientific publications or equivalent
Willingness to complement and collaborate with existing research units at the research center
Excellent English language skills, both written and spoken are a requirement due to the international nature of the institute and collaborations

Our Offer:

We work on the very latest issues that impact our society and are offering you the chance to actively help in shaping the change We support you in your work with:

A large research campus with green spaces, offering the best possible means for networking with colleagues and pursuing sports alongside work
Outstanding scientific and technical infrastructure
Creative and international team that conducts research at the frontiers of science
The Forschungszentrum Jülich is one of the largest research centres in Europe with excellent scientific equipment, including the fastest supercomputer in Europe, is located on a green campus, and near the cultural centres of Cologne, Düsseldorf and Bonn
A highly motivated group and an international and interdisciplinary working environment in one of the largest research institutions in Europe
The possibility to develop your own research program in line with the institute and center strategy
Flexible working hours in a full-time position with the option of slightly reduced working hours
30 days of annual leave and provision for days off between public holidays and weekends ( between Christmas and New Year)
Targeted services for international employees, through our International Advisory Service


We offer you an exciting and varied role in an international and interdisciplinary working environment. The position is for a fixed term of 2,5 years, with possible long-term prospects. Salary and social benefits will conform to the provisions of the Collective Agreement for the Public Service (TVöD-Bund), pay group EG 13, depending on the applicant’s qualifications and the precise nature of the tasks assigned to them.

In addition to exciting tasks and a collaborative working atmosphere at Jülich, we have a lot more to offer:

We welcome applications from people with diverse backgrounds, in terms of age, gender, disability, sexual orientation / identity, and social, ethnic and religious origin. A diverse and inclusive working environment with equal opportunities in which everyone can realize their potential is important to us.

We look forward to receiving your application by

Apply now

Questions about the offer?

Please feel free to contact us via our contact form.
Please note that for technical reasons we cannot accept applications by e-mail.

You can find helpful information on the application and selection process here. You can also find answers to frequently asked questions in our FAQs.



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