Director Medicinal Chemistry

vor 2 Wochen


Munich, Bayern, Deutschland PROTEROS biostructures GmbH Vollzeit 90.000 € - 120.000 € pro Jahr

Proteros is a privately held early-stage services provider in structure-based drug discovery with a cutting-edge discovery engine tailored to unlock even the most technically challenging targets. Proteros' work is built on scientific excellence and supports its clients to reach the right results and accelerate their overall research timelines. Proteros supports most of the world's 20 largest pharma companies and more than 250 pharmaceutical and biotech partners in the US, Europe and Japan.

YOUR MISSION

We are looking for a highly skilled and innovative Director Medicinal Chemistry to join our drug discovery team at Proteros Biostructures. The ideal candidate will have a strong background in organic chemistry, drug design, and molecular modeling, with a track record and passion for discovering and optimizing new therapeutic compounds. The Director Medicinal Chemistry will play a critical role in the early stages of drug discovery, working closely with biologists, enabling technology experts, and other chemists to design molecules that have the potential to become safe and effective medications. Primary responsibilities will include designing and planning of synthesis of novel chemical entities, analyzing structure-activity relationships (SAR), and optimizing lead compounds for potency, selectivity, and pharmacokinetic properties. Close collaboration with customers and internal Proteros teams and excellent communication are key for the successful candidate.

Responsibilities

  • Design and synthesize novel small molecules for drug discovery
  • Analyze structure-activity relationships (SAR) to optimize hit and lead compounds
  • Guide tailored screening library design for small molecule hit generation campaigns
  • Develop and improve synthetic routes for target molecules through external partners
  • Collaborate with cross-functional Proteros teams and its customers.
  • Leading project planning and decision-making processes
  • Present research findings to internal teams and external customers
  • Stay current with scientific literature and emerging technologies

Qualifications

  • Ph.D. in Medicinal Chemistry, Organic Chemistry, or related field
  • 10+ years of experience in pharmaceutical or biotech industry
  • Drug Discovery project leadership experience with a track record for delivery of drug candidates
  • Strong knowledge of synthetic organic chemistry
  • Familiarity with molecular modeling and cheminformatics tools
  • Excellent problem-solving and critical thinking skills
  • Strong written and verbal communication abilities
  • Ability to work independently and in a team environment
  • Detail-oriented with strong organizational skills

WHY US?

  • Detail-oriented with strong organizational skills
  • An innovative field of work in an exciting industry
  • A long-term, responsible position in a healthy, growing, and future-oriented company
  • Comprehensive onboarding to prepare you optimally for your area of responsibility
  • Multicultural teams and an open corporate culture
  • A competitive salary


  • Munich, Bayern, Deutschland PROTEROS biostructures GmbH Vollzeit 90.000 € - 120.000 € pro Jahr

    Proteros is a privately held early-stage services provider in structure-based drug discovery with a cutting-edge discovery engine tailored to unlock even the most technically challenging targets. Proteros' work is built on scientific excellence and supports its clients to reach the right results and accelerate their overall research timelines. Proteros...

  • Manager Manufacturing

    Vor 6 Tagen


    Munich, Bayern, Deutschland WuXi AppTec Vollzeit 60.000 € - 100.000 € pro Jahr

    WuXi Apptec GmbH based in Munich is a certifying and importing site for commercial and investigational drug products for the EU market. In the frame of the expansion of our activity we are looking for a Manager Manufacturing who will be the responsible for managing the manufacturing and import of medicinal products and investigational medicinal products in...


  • Munich, Bayern, Deutschland Medella Life Vollzeit 90.000 € - 120.000 € pro Jahr

    Job Purpose / SummaryThe Associate Director (RA) will lead regulatory strategy, submissions, and lifecycle maintenance for assigned products / projects in the European / German / Central Eastern Europe region. This role ensures compliance with regulatory requirements, supports product development from early phase through to post-marketing, and acts as the...


  • Munich, Bayern, Deutschland BioLabs Vollzeit 60.000 € - 90.000 € pro Jahr

    BioLabs founded in 2009 and headquartered in Cambridge, MA, USA, is the premier global network of co-working laboratory spaces for life science startups. We empower innovation by providing entrepreneurial scientists with premium, fully equipped lab and office spaces, along with exceptional access to capital and industry partners. Our rapidly expanding global...


  • Munich, Deutschland Biogen Vollzeit

    For our office in Munich (in a hybrid working model) we are recruiting for a **Associate Director, DACH Regional Drug Safety Lead (f/m/d)** The Associate Director, DACH Regional Drug Safety Lead (f/m/d) is responsible for leading the Drug Safety departments for the DACH region (Germany, Austria, Switzerland), including line management of the local team,...


  • Munich, Deutschland Proclinical Vollzeit

    Proclinical are recruiting an Associate Director, Quality Assurance (RP) for a biotech organisation. This role is on a permanent basis and is located in Munich. The client is focused on creating, manufacturing and commercialising transformative remedies for those who suffer from serious illnesses. **Responsibilities**: - Supervise GMP/GXP compliance to...


  • Munich, Deutschland Proteros biostructures GmbH Vollzeit

    YOUR MISSION - You will be a member of our interdisciplinary teams alongside colleagues from project management, protein production, protein crystallography, medicinal and computational chemistry - Within these experienced teams you will be responsible for developing biochemical and biophysical approaches to support internal and customer early drug discover...

  • Principal Scientist

    Vor 7 Tagen


    Munich, Deutschland BI Pharma GmbH&Co.KG Vollzeit

    **The Position**: **Tasks & responsibilities**: - In your new role you will lead a highly motivated and experienced team as Principal Scientist (head of laboratory) with the focus to support our retinopathy pipeline. - You will be responsible for the in vivo testing of new molecular entities (e.g. small molecules, peptides, antibodies, si/saRNA approaches)...

  • Scientific Director

    Vor 7 Tagen


    Munich, Deutschland Proteros biostructures GmbH Vollzeit

    YOUR MISSION - Scientific lead for an external multi project collaboration - Lead teams with clear guidance, critical assessment and pragmatic recommendations and securing quality of science, excellence in execution and consistency in decisions - Ensure cross-functional collaboration between disciplines - Help advance the integration of capabilities and...


  • Munich, Deutschland BI Pharma GmbH&Co.KG Vollzeit

    **The Position**: Join a leading team in the field of "Drug Discovery Sciences" as a Senior/Principal Scientist in the in vitro ADME team. This role is a part of a global Research DMPK group and offers an exciting opportunity to be an integral part of multidisciplinary research teams. You will have the chance to actively contribute to the discovery of...


  • Munich, Deutschland Proteros biostructures GmbH Vollzeit

    YOUR MISSION - You will be a member of our interdisciplinary teams alongside colleagues from project management, protein production, protein crystallography, medicinal and computational chemistry. - Within these experienced teams you will be responsible for developing biochemical and biophysical approaches to support internal and customer early drug discover...


  • Munich, Deutschland Proteros biostructures GmbH Vollzeit

    YOUR MISSION - You will be a member of our interdisciplinary teams alongside colleagues from project management, protein production, protein crystallography, medicinal and computational chemistry - Within these experienced teams you will be responsible for developing biochemical and biophysical approaches to support internal and customer early drug discover...


  • Munich, Deutschland MSD Vollzeit

    **Job Description**: Our Manufacturing & Supply Division is dedicated to being the most trusted supplier of biopharmaceuticals worldwide. Our facilities, along with our external contractors, suppliers, and partners, create a reliable global manufacturing network that’s devoted to delivering a high-quality, reliable supply to customers and patients on time,...

  • Associate Director

    vor 2 Wochen


    Munich, Deutschland Hexal AG Vollzeit

    Sandoz is going through an exciting and transformative period as a global leader and pioneering provider of sustainable Generic and Biosimilar medicines. Now as an independently listed company, Sandoz aims to increase its strategic focus, operate with greater agility, set clearer business objectives, enhance shareholder returns, and strengthen its culture...