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The Faculty of Medicine is one of the four founding faculties of the Eberhard Karls University of Tübingen. With its non-clinical facilities as well as its research and teaching area corresponding to the organisational units of the University Hospital, it is one of the largest medical training and research institutions in Baden-Württemberg.
The Institute of Clinical Anatomy and Cell Analysis, Tübingen University, AG Glomb, invites applications for a PhD position. We are looking for a highly motivated PhD candidate with an interest in neuronal cell biology. Our lab is interested in understanding the mechanisms that underly slow axonal transport. This transport mechanism conveys hundreds of cytoplasmic proteins from the cell body into the periphery of the neurite. We recently developed a fluorescent based labeling strategy to visualize and molecularly dissect this transport mechanism in single neurons of the invertebrate C.elegans. This project will focus on further dissecting the composition of transport packages of this pathway and ask for the regulatory mechanisms underlying it. We utilize in vivo microscopy in C.elegans, which we combine with super-resolution microscopy, genetic screens, genome editing, molecular biology, and biochemical assays. You do not require any experience with the work on C.elegans/Nematodes.
Activities And Responsibilities
- Design, perform and interpret cell biological experiments in C. elegans
- Generate reagents to study neuronal cell biology based on different molecular biological tools
- Complement your in vivo findings by biochemical approaches
- Present your results in lab meetings, seminars and at conferences
- Support training activities for medical and life science students
Qualification profile
- Master degree (or equivalent) in Molecular Biology, Cell Biology, Biochemistry, Molecular Medicine or a related field
- Able to drive projects independently with high curiosity and critical thinking
- Solid knowledge in cell biology with a high interest in microscopy
- Team player with great communication and writing skills
Benefits
- A friendly, open and collaborative working environment with an international team
- A great model system (C.elegans) for neuronal cell biology and beyond
- Intensive mentoring and support for your scientific development
- Multidisciplinary research environment with access to state of the art core facilities
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