Postdoctoral Researcher in Functional Cancer

**Reference number**:2024-0314** - Freiburg- Full-time- DKTK partner site Freiburg - Cancer Research*** **_“Research for a life without cancer" is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and look for new cancer prevention strategies. We develop new methods with which tumors can be diagnosed more precisely and cancer patients can be treated more successfully. Every contribution counts - whether in research, administration or infrastructure. This is what makes our daily work so meaningful and exciting._** Together with university partners at seven renowned partner sites, we have established the German Cancer Consortium (DKTK). For the Division of **Cancer Research** at the **DKTK partner site Freiburg** we are seeking from January 2025 a The Division of Cancer Research at the University Medical Center Freiburg is focused on functional cancer genomics and especially the high-throughput characterization of mutations in cancer genes for their impact on tumorigenesis, signaling activation and targeted therapy response (e.g. Nat Commun 2019, Nat Cell Biol 2020, Nat Commun 2024, Nat Genet 2024). **YOUR TASKS**: We are seeking a postdoctoral fellow with significant and published experience in the area of molecular biology and / or cancer research, ideally in cancer genetics. The core project of the postdoctoral fellow will be the functional characterization and analysis of genetic alterations in cancer in high throughput. Research questions will include the mutational impact at the cellular and molecular level and their mechanistic consequences. An innovative screen using CRISPR site-directed mutagenesis shall unravel their impact on human cells. Comprehensive resources as well as established protocols to build on are available. Jointly with the division head, new projects within the focus area of the lab can also be developed and supported to allow the growth into scientific maturity and independence. **YOUR PROFILE**: You are a highly motivated, ambitious postdoctoral fellow with a PhD / Dr. rer. nat. in a life science field and are eager to pursue and lead research projects in functional tumor genetics and molecular biology of cancer, including high-throughput approaches and precision genome editing, with ambition, creativity, independence and team spirit. You have published experience in techniques of cellular and molecular biology or cancer research. Practical knowledge of bioinformatics would be welcome. You work efficiently, goal-oriented and accurate, have a deep interest in research and are proficient in English. **WE OFFER**: **Excellent framework conditions: state-of-the-art equipment and opportunities for international networking at the highest level** ***: **Remuneration according to TV-L incl. occupational pension plan and capital-forming payments** ***: **30 days of vacation per year** ***: **Flexible working hours** ***: **Possibility of part-time work** ***: **Family-friendly working environment** ***: **Sustainable travel to work: subsidized Germany job ticket** ***: **Our Corporate Health Management Program offers a holistic approach to your well-being** ***: **Develop your full potential: access to the DKFZ International Postdoc Program and DKFZ Career Service with targeted offers for your personal development to further develop your talents** ***: **ARE YOU INTERESTED?**: Then become part of the DKFZ and join us in contributing to a life without cancer **Contact**: Prof. Dr. Sven Diederichs Phone: +49(0)761 270-77571 **Duration**: The position is initially limited to 2 years with the possibility of prolongation.**Application Deadline**:07.11.2024