Scientist - Functional Genomics and Clinical Discovery

**Reference number**:2025-0006** - Heidelberg - Full-time, Part-time - Precision Sarcoma Research **_“Research for a life without cancer" is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and look for new cancer prevention strategies. We develop new methods with which tumors can be diagnosed more precisely and cancer patients can be treated more successfully. Every contribution counts - whether in research, administration or infrastructure. This is what makes our daily work so meaningful and exciting._** The **Precision Sarcoma Research Group** is seeking for the next possible date a Bone and soft-tissue sarcomas are a diverse group of rare and aggressive malignancies arising from mesenchymal tissues. These cancers are characterized by low incidence rates, delayed diagnoses, limited treatment options, and poor clinical outcomes, highlighting an urgent need for innovative therapies and collaborative research efforts to address their unique challenges. **YOUR TASKS**: **Experimental Design, Execution, and Data Analysis**: - Perform high-throughput screening to investigate gene function and regulation - Analyze large-scale genomic datasets using bioinformatics tools, integrating multi-omics data to extract biological insights - Collaborate with computational biologists for advanced data interpretation **Research Development**: - Stay updated on the latest advancements in genomics and molecular biology - Identify and propose innovative approaches to address research challenges **Collaborative Engagement and Leadership**: - Work closely with interdisciplinary teams, including biologists, bioinformaticians, and clinicians - Present findings at lab meetings, institutional seminars, and scientific conferences - Mentor and guide graduate and undergraduate students in experimental techniques and data analysis **YOUR PROFILE**: - PhD or equivalent degree in cancer biology, immunology, biotechnology, molecular biology, or related fields - Extensive expertise in mammalian cell culture, molecular biology techniques, and protein detection methods - Proven experience in designing, executing, and analyzing data from CRISPR/Cas9 screens, ACT-seq, ChIP-seq, Hi-C, or similar epigenetic profiling methods - Proficiency in R programming for statistical analysis and data visualization is highly desirable - Strong publication record, including lead authorships, with experience in collaborative research and supervision of students or interns - Comprehensive knowledge of cancer biology, immunology, and cancer genomics, maintained through rigorous literature review and applied to data interpretation and project advancement - Demonstrated ability to work both independently and collaboratively, with high self-initiative, a strong work ethic, and team-oriented mindset - Good knowledge of English is required for the job **WE OFFER**: **Excellent framework conditions: state-of-the-art equipment and opportunities for international networking at the highest level** **30 days of vacation per year** **Flexible working hours** **Remuneration according to TV-L incl. occupational pension plan and capital-forming payments** **Possibility of part-time work** **Family-friendly working environment** **Sustainable travel to work: subsidized Germany job ticket** **Unleash your full potential: targeted offers for your personal development to further develop your talents** **Our Corporate Health Management Program offers a holistic approach to your well-being** **ARE YOU INTERESTED?**: Then become part of the DKFZ and join us in contributing to a life without cancer **Contact**: Dr. Priya Chudasama Phone: +49 6221 42 1600 **Duration**: The position is initially limited to 2 years with the possibility of prolongation. **Application Deadline**:30.01.2025