Principal Systems Pharmacology Expert
vor 2 Wochen
**THE POSITION**:
Boehringer Ingelheim (BI) is expanding its Systems Pharmacology team in the global Translational Medicine & Clinical Pharmacology Data Science (TMCP DS) group in Biberach and Ingelheim, Germany.
The mandate of TMCP DS is to maximize knowledge generation from TMCP data to enhance disease understanding through integrative and holistic data analyses. By this means, we collaborate with our neighboring functions in critical decision making along planning and execution of our clinical development programs.
In addition, acting as a Data Science Lead (DSL) you represent our various Data Science functions in project team meetings. In your role as a DSL you will have the chance to shape the data science strategy of drug development projects starting prior to first-in-man trials up to regulatory submission and beyond.
This position is part time eligible with 80 %.
**Tasks & responsibilities**:
- In your new role, you will design the Systems Pharmacology strategy to support clinical development teams to understand drug-patient-disease relationships and maximize the therapeutic benefit of investigational products.- You will independently engage with stakeholders to identify opportunities for systems pharmacology analysis, proactively plan and execute the analysis and present results to relevant clinical and pre-clinical teams.- In addition, you will contribute as expert leader in an interdisciplinary environment, partnering with pharmacometricians, clinical pharmacologists, biomarker experts and collaborating with various functions from our Research and Medical departments to plan, design, execute and appropriately document relevant analyses, thereby supporting internal decision making and ultimately leading to successful approvals.-
- With your expertise, you will implement first-hand (or manage CRO implementation of) mechanistic disease models which integrate public and proprietary datasets to improve understanding of the underlying biology in relation to proposed mechanisms of action, biomarkers and clinical endpoints.- As an experienced Systems Pharmacologist, you will foster internal innovation and mentor junior colleagues.
**Requirements**:
- PhD. in Systems Pharmacology, Engineering, Mathematics, Statistics, Physics, Computer Sciences, Bioinformatics or a related life sciences field-
- Demonstrated expert knowledge of the full spectrum of systems pharmacology modeling activities and essential knowledge of biology, physiology and pharmacology- Understanding of Pharmacometric and Bioinformatic analyses and their contributions to clinical development- Proficient use of programming and data analysis software (e.g. R, MATLAB, Python, Julia) and modeling frameworks (e.g. SimBiology, SBML)- Team player with demonstrated success working in cross-functional project teams (global, multicultural and partially remote).- Excellent verbal and written communication skills in English, with expertise in production of formal modeling and simulation reports, as well as in the development of best-practice documents.- Experience in one of Boehringer Ingelheim’s key therapeutic areas is a plus (Oncology, Inflammation, Cardio-Renal-Metabolism, CNS, Retinal Health)
**READY TO CONTACT US?**:
Please contact our HR Direct Team, Tel: +49 (0) 6132 77-3330.
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