Aktuelle Jobs im Zusammenhang mit Master Thesis for Multiplex digital PCR using High-Density Microwell Arrays - Freiburg im Breisgau - Hahn-Schickard-Gesellschaft für angewandte Forschung e.V.
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Master Thesis for Multiplex digital PCR using High-Density Microwell Arrays
vor 8 Stunden
Vision to Products Welcome to Hahn-Schickard: The research center for innovative microsystems technology. With a team of over 300 employees, we transform ideas into cross-industry solutions - from conception to production at four locations in Baden-Württemberg. At our Freiburg site, the emphasis is on developing analytical solutions in microsystems technology, particularly for point-of-care diagnostics. For the area of Microfluidic Platforms in Freiburg, we offer from 01.04.2026 or later a Master Thesis for Multiplex digital PCR using High-Density Microwell Arrays (m/f/x) Aim of the thesis Multiplexing in digital PCR is often limited by "partition-specific competition" in commercial devices (≈25,000 partitions), where co-encapsulated targets compete for reagents.The goal of the thesis is to demonstrate how a LabDisk, with its high-density array of 250,000 microwells, eliminates this competition to ensure robust quantification of liquid biopsy targets like KRAS. Your Tasks Assay Development: Implement a multiplex Mediator Probe dPCR assay on the LabDisk.Comparison: Validate LabDisk performance against commercial dPCR systems.Data Analysis: Analyze high-density multiplex data. Your profile Studies: Biochemistry, Biotechnology, Molecular Biology, Medical Engineering, or a related STEM discipline.Skills: Lab experience (pipetting/ PCR) and interest in bioanalytics.Work Style: Independent and structured.Language: Good English or German Our offer to you Flexible working hoursInsights into current digital PCR development for molecular diagnosticsClose supervision and the opportunity to contribute your own ideasA young and dynamic teamAn attractive workplace in a modern, excellently equipped research institute that is close to industryParticipation in first-class health programmes such as HansefitSubsidy for mealsSubsidies for public transport Your Application Mr. Dr. Peter Jülg will be pleased to answer any question you may have. Peter.Juelg@hahn-schickard.de / Tel.: +49 761 203-95421 If you are interested, please send us your complete application documents (motivation letter/resume+CV/certificates/transcript of records), stating the reference number 26/3240/02 in a complete PDF document and naming the job portal here online via the application form. The decision is made directly by the division.