PhD Researcher

vor 4 Wochen


Leipzig, Sachsen, Deutschland Helmholtz-Zentrum für Umweltforschung GmbH - UFZ Vollzeit

We are seeking a highly motivated PhD Researcher to join our team at the Helmholtz Centre for Environmental Research (UFZ). The successful candidate will work on a DFG-funded project to study the metabolic interaction within a microbiome model system, focusing on the production of nucleotides.

The project aims to decipher the role of nucleotides in the human microbiome model system SIHUMIx. The successful candidate will cultivate the SIHUMIx consortium in anaerobic continuous bioreactors and manipulate specific species by the CRISP/CAS approach.

The tasks include characterizing the effects of modified gene expression of selected species on the metabolomic level of the various species and the overall community metabolism by mass-spectrometry-based targeted and untargeted metabolomics and metaproteomics.

The successful candidate will integrate the omics-results with bioinformatic approaches and also with the results from genome-based metabolic modelling to identify pathways of metabolic regulation within the various species and in the species-species interaction.

We offer excellent supervision and optimal professional and interdisciplinary qualification through our HIGRADE graduate programme. The freedom to master even the most demanding challenges between basic research and practical application.

The opportunity to work in interdisciplinary, international teams and benefit from a wide range of perspectives. First class integration into national and international research networks to work together on global challenges.

Excellent research infrastructure and research data management to optimally support your work. A wide range of options for balancing care responsibilities and work through our family office.

Competent support and advice for international colleagues arriving at the UFZ from the 'International Office'. Special annual payment, capital-forming benefits and subsidised Deutschland-Job-Ticket.

A workplace in a vibrant region with a high life quality and social and cultural diversity.

Your profile should include a M.Sc. degree (or near completion) in biochemistry, microbiology, bioinformatics or related fields. Experience in cultivation of bacteria.

Profound knowledge of microbiology. Strong interest in mass-spectrometry-based analysis of metabolites and proteins. Strong interest in bioinformatics.

Excellent English skills. Ability to organize and prioritize work efficiently.



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