PhD Researcher Position in Microbiome Modeling

Vor 7 Tagen

Leipzig, Sachsen, Deutschland Helmholtz Centre for Environmental Research Vollzeit

The Helmholtz Centre for Environmental Research

We are seeking a PhD Researcher to study the metabolic interaction within a microbiome model system, focusing on the production of nucleotides in the Department of Molecular Toxicology.

Your Responsibilities

  • Cultivate the SIHUMIx consortium in anaerobic continuous bioreactors and manipulate specific species by the CRISP/CAS approach.
  • Characterize the effects of modified gene expression of selected species on the metabolomic level of the various species and the overall community metabolism by mass-spectrometry based targeted and untargeted metabolomics and metaproteomics.
  • Integrate the omics-results with bioinformatic approaches and also with the results from genome-based metabolic modelling to identify pathways of metabolic regulation within the various species and in the species-species interaction.
  • Participate in laboratory group meetings including presentation of results.
  • Present your results at international conferences and prepare publications in peer-reviewed scientific journals.

We Offer

  • Excellent supervision and optimal professional and interdisciplinary qualification through our HIGRADE graduate programme.
  • The freedom to master even the most demanding challenges between basic research and practical application.
  • The opportunity to work in interdisciplinary, international teams and benefit from a wide range of perspectives.
  • First-class integration into national and international research networks to work together on global challenges.
  • Excellent research infrastructure and research data management to optimally support your work.
  • A wide range of options for balancing care responsibilities and work through our family office.
  • Competent support and advice for international colleagues arriving at the UFZ from the 'International Office'.
  • Special annual payment, capital-forming benefits and subsidised Deutschland-Job-Ticket.
  • A workplace in a vibrant region with a high life quality and social and cultural diversity.

Your Profile

  • M.Sc degree (or near completion) in biochemistry, microbiology, bioinformatics or related fields.
  • Experience in cultivation of bacteria.
  • Profound knowledge of microbiology.
  • Strong interest in mass-spectrometry-based analysis of metabolites and proteins.
  • Strong interest in bioinformatics.
  • Excellent English skills.
  • Ability to organize and prioritize work efficiently.

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