Senior Oligonucleotide Synthesis Specialist

vor 1 Woche


Kulmbach, Bayern, Deutschland LGC Axolabs Vollzeit
Job Title: Senior Oligonucleotide Synthesis Specialist

We are seeking an experienced Senior Oligonucleotide Synthesis Specialist to join our innovative R&D team in Oligonucleotide Chemistry. As a key member of our team, you will be responsible for developing innovative synthetic approaches for complex oligonucleotide formats, including conjugates with fatty acids, peptides, and antibodies.

Key Responsibilities:

  • Develop and optimize synthetic and downstream processing routes for complex oligonucleotide formats.
  • Collaborate with the team to design and execute experiments that optimize lead oligonucleotide drug candidates.
  • Take on responsibility for customer order projects after a thorough training period.
  • Support the Department Head in project planning, client communication, and report writing.
  • Analyze experimental data, interpret results, and present findings internally, to customers, or at international conferences.

Qualifications:

  • Hands-on experience in oligonucleotide synthesis via automated solid-phase methodologies, complemented by a Ph.D. in Chemistry or Biochemistry, or equivalent experience.
  • Prior experience in ligation chemistry (enzymatic and/or chemical) is required.
  • Proficient in conjugation and purification technologies, with expertise in HPLC, LC-MS, UV spectroscopy, and endotoxin measurement and control.
  • Strong oral and written communication skills in English, ideally also in German, with a keen ability to maintain detailed lab notebooks and reports.

Your Benefits:

  • Comprehensive onboarding and mentoring for a successful start.
  • Permanent employment contract.
  • Responsible tasks and individual development and career opportunities in an innovative, international company.
  • An open corporate culture that values integrity, respect, and a passion for forward-thinking, creative solutions.

We look forward to receiving your application in English.



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