Scientist - DNA, RNA, and Oligonucleotide Synthesis Expert

vor 4 Wochen


Kulmbach, Bayern, Deutschland LGC Axolabs Vollzeit
Job Title: Scientist - DNA, RNA, and Oligonucleotide Synthesis Expert

We are seeking an experienced and motivated scientist to join our innovative R&D team in oligonucleotide chemistry. As a key member of our team, you will be responsible for developing innovative synthetic approaches for complex oligonucleotide formats.

Key Responsibilities:
  • Develop and optimize synthetic routes for complex oligonucleotide formats, including conjugates with fatty acids, peptides, and antibodies.
  • Collaborate with the team to design and execute experiments that optimize lead oligonucleotide drug candidates, focusing on potency, selectivity, stability, and pharmacokinetic properties.
  • Take on responsibility for customer order projects after a thorough training period.
  • Support the Department Head in project planning, client communication, and report writing.
  • Analyze experimental data, interpret results, and present findings internally, to customers, or at international conferences.
  • Guide and coach junior staff members in the oligonucleotide synthesis laboratory.
Qualifications:
  • Hands-on experience in oligonucleotide synthesis via automated solid-phase methodologies, complemented by a Ph.D. in Chemistry or Biochemistry, or equivalent experience.
  • Prior experience in ligation chemistry (enzymatic and/or chemical) is desired.
  • Proficient in conjugation and purification technologies, with expertise in HPLC, LC-MS, UV spectroscopy, and endotoxin measurement and control.
  • Strong oral and written communication skills in English, ideally also in German, with a keen ability to maintain detailed lab notebooks and reports.
  • A reliable, dedicated working style characterized by a focus on quality, dedication, and excellent communication skills.
What We Offer:
  • Comprehensive onboarding and mentoring for a successful start.
  • Permanent employment contract.
  • Responsible tasks and individual development and career opportunities in an innovative, international company.
  • An open corporate culture that values integrity, respect, and a passion for forward-thinking, creative solutions.
  • Company pension scheme and attractive employer subsidies, such as JobRad, as well as corporate benefits.
  • Extensive employee offerings related to health management, as well as online options for childcare and educational support.
  • 30 days of annual leave.
  • Relocation assistance for candidates from outside the region.
  • 100% coverage of the Jobticket (Deutschlandticket) or a free parking space in the adjacent parking garage.

We look forward to receiving your application in English.



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