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Kulmbach, Bayern, Deutschland LGC Axolabs VollzeitJob Title: Scientist - DNA, RNA, and Oligonucleotide Synthesis SpecialistWe are seeking an experienced and motivated scientist to join our innovative R&D team in oligonucleotide chemistry. As a key member of our team, you will be responsible for developing innovative synthetic approaches for complex oligonucleotide formats.Key Responsibilities:Develop and...
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Kulmbach, Deutschland LGC Axolabs Vollzeit**Company Description** Axolabs specialises in a new class of drugs whose active ingredients are chemically derived from DNA or RNA. They are called oligonucleotide or nucleic acid therapeutics. We use our many years of expertise to help our clients make them a success. Some of these drugs have already been approved and are being used successfully against...
Senior Oligonucleotide Synthesis Specialist
vor 2 Monaten
We are seeking an experienced and motivated scientist to develop innovative synthetic approaches for complex oligonucleotide formats.
About the RoleThis is an exciting opportunity to join our innovative R&D team in oligonucleotide chemistry and contribute to the development of new synthetic routes for complex oligonucleotide formats.
Key Responsibilities- Develop innovative synthetic and downstream processing routes for complex oligonucleotide formats, including conjugates with fatty acids, peptides, and antibodies.
- Collaborate with the team to design and execute experiments that optimize lead oligonucleotide drug candidates, focusing on potency, selectivity, stability, and pharmacokinetic properties.
- Take on responsibility for customer order projects after a thorough training period.
- Support the Department Head in project planning, client communication, and report writing.
- Analyze experimental data, interpret results, and present findings internally, to customers, or at international conferences. Contribute to technical reports and manuscripts for publication in peer-reviewed journals.
- Guide and coach junior staff members in the oligonucleotide synthesis laboratory.
- Hands-on experience in oligonucleotide synthesis via automated solid-phase methodologies, complemented by a Ph.D. in Chemistry or Biochemistry, or equivalent experience.
- Prior experience in ligation chemistry (enzymatic and/or chemical) is desired.
- Proficient in conjugation and purification technologies, with expertise in HPLC, LC-MS, UV spectroscopy, and endotoxin measurement and control.
- Strong oral and written communication skills in English, ideally also in German, with a keen ability to maintain detailed lab notebooks and reports.
- A reliable, dedicated working style characterized by a focus on quality, dedication, and excellent communication skills.
- Comprehensive onboarding and mentoring for a successful start.
- Permanent employment contract.
- Responsible tasks and individual development and career opportunities in an innovative, international company.
- An open corporate culture that values integrity, respect, and a passion for forward-thinking, creative solutions.
- Company pension scheme and attractive employer subsidies, such as JobRad, as well as corporate benefits.
- Extensive employee offerings related to health management, as well as online options for childcare and educational support.
- 30 days of annual leave.
- Relocation assistance for candidates from outside the region.
- 100% coverage of the Jobticket (Deutschlandticket) or a free parking space in the adjacent parking garage.
We look forward to receiving your application in English.