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vor 1 Monat
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Senior Research Scientist
vor 2 Monaten
We are seeking a highly skilled and motivated Staff Scientist to join our team at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie. The successful candidate will be responsible for operating and maintaining our state-of-the-art mass spectrometry and proteomics technology platform.
Key Responsibilities:- Optimize and apply various quantitative proteomic methods, including SILAC, TMT, and label-free approaches with DDA and DIA.
- Develop and implement structural and chemical proteomic methods, such as cross-linking MS and proximity biotinylation.
- Analyze post-transcriptional modifications, with a focus on phosphorylation.
- Support users of the MS facility throughout the MS workflow, from sample preparation to data analysis.
- Collaborate with technicians and engineers to maintain and operate the LC/MS instruments.
- Excellent knowledge of quantitative proteomic techniques.
- Strong experience with DDA and DIA acquisition and data analysis.
- Expertise in handling LC/MS instruments, particularly Thermo Fisher Orbitrap Tribrid and Exploris mass spectrometers.
- Experience in cross-linking MS or other structural and chemical proteomic methods is advantageous.
- Ability to accurately and reliably document and present scientific data.
- Strong communication skills and proficiency in English.
The mass spectrometry and proteomics technology platform at the FMP is a dynamic and collaborative environment, providing MS services to research groups within and outside of the FMP. The platform hosts a range of state-of-the-art mass spectrometers, including two Orbitrap Exploris 480, LTQ-Orbitrap Fusion Lumos, one LTQ-Orbitrap Fusion, and one LTQ-Orbitrap Elite, all equipped with nano-UPLC systems.
What We Offer:We offer a competitive salary and benefits package, as well as opportunities for professional growth and development. The successful candidate will work closely with our international team of scientists and technical assistants, ensuring optimized operation of the MS instruments and setting up proteomics experiments.
We are an equal opportunities employer and welcome applications from candidates with diverse backgrounds and experiences. We offer a dynamic and inclusive work environment, with a strong focus on collaboration and teamwork.
