Microbiome Interaction Specialist

vor 4 Wochen

Halle, Sachsen-Anhalt, Deutschland Helmholtz-Zentrum für Umweltforschung GmbH - UFZ Vollzeit

The Helmholtz Centre for Environmental Research (UFZ) is seeking a highly motivated PhD Researcher to study the metabolic interaction within a microbiome model system, focusing on the production of nucleotides. The project aims to decipher nucleotides' role in the human microbiome model system SIHUMIx.

Key Responsibilities
  • Cultivate the SIHUMIx consortium in anaerobic continuous bioreactors and manipulate specific species by the CRISP/CAS approach
  • Characterize the effects of modified gene expression of selected species on the metabolomic level of the various species and the overall community metabolism by mass-spectrometry-based targeted and untargeted metabolomics and metaproteomics
  • Integrate the omics-results with bioinformatic approaches and also with the results from genome-based metabolic modelling to identify pathways of metabolic regulation within the various species and in the species-species interaction
  • Participate in laboratory group meetings including presentation of results
  • Present your results at international conferences and prepare publications in peer-reviewed scientific journals
Requirements
  • M.Sc. degree (or near completion) in biochemistry, microbiology, bioinformatics or related fields
  • Experience in cultivation of bacteria
  • Profound knowledge of microbiology
  • Strong interest in mass-spectrometry-based analysis of metabolites and proteins
  • Strong interest in bioinformatics
  • Excellent English skills
  • Ability to organize and prioritize work efficiently

The UFZ offers a dynamic and interdisciplinary work environment with opportunities for professional and personal growth. We are committed to diversity and equal opportunities for all employees.

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